Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
E126026-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $9.90 | |
E126026-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $11.90 | |
E126026-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $15.90 | |
E126026-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $23.90 | |
E126026-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $57.90 | |
E126026-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $211.90 |
Synonyms | EDOXABAN|480449-70-5|912273-65-5|DU-176|UNII-NDU3J18APO|NDU3J18APO|DU-176b|CHEBI:85973|N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide|CHEMBL1269025|HS |
---|---|
Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: IC50 Value:N/A Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammator |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of coagulation factor X |
Note | 5mg,50mg、10mg卖完停产,不再备货 |
Product Description | Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide |
---|---|
INCHI | InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1 |
InChi Key | HGVDHZBSSITLCT-JLJPHGGASA-N |
Canonical SMILES | CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C |
Isomeric SMILES | CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C |
PubChem CID | 10280735 |
Molecular Weight | 548.06 |
CAS Registry No. | 480449-70-5 |
---|---|
PubChem CID | 10280735 |
Wikipedia | Edoxaban |
ChEMBL Ligand | CHEMBL1269025 |
PEP | edoxaban |
Reactome Reaction | R-HSA-9015122, R-HSA-9015111 |
Reactome Drug | R-ALL-9038742 |
DrugCentral Ligand | 4897 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2404315 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404316 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404317 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404318 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404319 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404325 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404327 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404401 | Certificate of Analysis | Jun 22, 2024 | E126026 |
G2404402 | Certificate of Analysis | Jun 22, 2024 | E126026 |
B1526034 | Certificate of Analysis | Jun 12, 2024 | E126026 |
Solubility | 25°C: DMSO |
---|
Pictogram(s) | GHS08 |
---|---|
Signal | Warning |
Hazard Statements | H373:Causes damage to organs through prolonged or repeated exposure |
Precautionary Statements | P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P319:Get medical help if you feel unwell. |
Starting at $241.90