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Edoxaban - ≥98%, high purity , CAS No.480449-70-5, Inhibitor of coagulation factor X

  • Moligand™
  • ≥98%
Item Number
E126026
Grouped product items
SKUSizeAvailabilityPrice Qty
E126026-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
E126026-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$11.90
E126026-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$15.90
E126026-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$23.90
E126026-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$57.90
E126026-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$211.90
View related series
coagulation factor X Inhibitor

Basic Description

SynonymsEDOXABAN|480449-70-5|912273-65-5|DU-176|UNII-NDU3J18APO|NDU3J18APO|DU-176b|CHEBI:85973|N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide|CHEMBL1269025|HS
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsDescription: IC50 Value:N/A Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammator
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of coagulation factor X
Note5mg,50mg、10mg卖完停产,不再备货
Product Description

Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.

Associated Targets

F10 Tclin Coagulation factor X 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ENGASE Tchem Cytosolic endo-beta-N-acetylglucosaminidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
INCHI InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
InChi Key HGVDHZBSSITLCT-JLJPHGGASA-N
Canonical SMILES CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C
Isomeric SMILES CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C
PubChem CID 10280735
Molecular Weight 548.06

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2404315Certificate of AnalysisJun 22, 2024 E126026
G2404316Certificate of AnalysisJun 22, 2024 E126026
G2404317Certificate of AnalysisJun 22, 2024 E126026
G2404318Certificate of AnalysisJun 22, 2024 E126026
G2404319Certificate of AnalysisJun 22, 2024 E126026
G2404325Certificate of AnalysisJun 22, 2024 E126026
G2404327Certificate of AnalysisJun 22, 2024 E126026
G2404401Certificate of AnalysisJun 22, 2024 E126026
G2404402Certificate of AnalysisJun 22, 2024 E126026
B1526034Certificate of AnalysisJun 12, 2024 E126026

Chemical and Physical Properties

Solubility25°C: DMSO

Safety and Hazards(GHS)

Pictogram(s) GHS08
Signal Warning
Hazard Statements

H373:Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P501:Dispose of contents/container to ...

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P319:Get medical help if you feel unwell.

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