| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| E427156-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
| Synonyms | 96020-91-6|Eflornithine hydrochloride hydrate|Eflornithine hydrochloride monohydrate|Vaniqa|Eflornithine HCl|dfmo|MDL 71,782 A|Eflornithine HCl hydrate|Eflornithine hydrochloride [USAN]|UNII-4NH22NDW9H|4NH22NDW9H|RMI-71782|2-(Difluoromethyl)-DL-ornithine |
|---|---|
| Specifications & Purity | 10mM in Water |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Eflornithine(Difluoromethylornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours. A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis. Inhibits B16 melanoma-induced angiogenesis in ovo and proliferation of vascular endothelial cells in vitro. |
| IUPAC Name | 2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrate;hydrochloride |
|---|---|
| INCHI | InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2 |
| InChi Key | FJPAMFNRCFEGSD-UHFFFAOYSA-N |
| Canonical SMILES | C(CC(C(F)F)(C(=O)O)N)CN.O.Cl |
| Isomeric SMILES | C(CC(C(F)F)(C(=O)O)N)CN.O.Cl |
| RTECS | RM2981900 |
| Alternate CAS | 70052-12-9 |
| PubChem CID | 441361 |
| Molecular Weight | 236.65 |
| Reaxy-Rn | 13338246 |
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| Sensitivity | heat sensitive |
|---|---|
| Melt Point(°C) | 183°C(lit.) |
| RTECS | RM2981900 |
|---|---|
| Reaxy-Rn | 13338246 |
| Merck Index | 3522 |
