a tyrosine kinase inhibitor that inhibits human FGFR-1, PDGFR-β, c-Scr, & EGFR
Basic Description
Specifications & Purity
≥97%
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Product Description
EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor is a cell-permeable and reversible protein tyrosine kinase inhibitor that inhibits human Flg (FGFR-1), PDGFR-β, c-Scr, and EGFR, meanwhile exhibiting minimal activity against InsR, PKC, or CDK4/Cyclin D1. Inhibition by EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor is shown to be noncompetitive in the case of c-Src, but ATP-competitive in the case of Flg (FGFR-1), PDGFR-β, and EGFR.
