EGFR-IN-69 - 10mM in DMSO, high purity , CAS No.2433837-65-9(DMSO)

  • 10mM in DMSO
Item Number
E654893
Grouped product items
SKUSizeAvailabilityPrice Qty
E654893-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$435.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsEGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) re
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) research

IC50& Target:EGFR L858R/T790M/C797S 4.3 ± 0.9 nM (IC 50 ) EGFR L858R/T790M 6.6 ± 0.8 nM (IC 50 ) EGFR del19 T790M C797S 25.6 ± 7.5 nM (IC 50 ) EGFR WT 816.0 ± 82 nM (IC 50 )

Names and Identifiers

Canonical SMILES O=S(N1C=C(C2=NC(NC3=CC(Cl)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3OC)=NC=C2Cl)C6=C1C=CC=C6)(CC)=O
Molecular Weight 658.64

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