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Eicosa-11Z,14Z-dienoic Acid - 98%, high purity , CAS No.2091-39-6
a polyunsaturated lipid analog of arachidonic acid that inhibits calcineurin
Basic Description Synonyms 11,14-Eicosadienoic acid|2091-39-6|Eicosadienoic acid|(11E,14E)-icosa-11,14-dienoic acid|11, 14-icosadienoic acid|11(Z),14(Z)-Eicosadienoic Acid|C20:2n-6,9|eicosa-11z,14z-dienoic acid|11,14-Eicosadienoicacid|11C 14C-Eicosadienoic Acid|SCHEMBL278058|11,14- Specifications & Purity 98% Storage Temp Protected from light,Store at -20°C Shipped In Ice chest + Ice pads Product Description Eicosa-11Z,14Z-dienoic acid is a polyunsaturated lipid analog of arachidonic acid. It has been shown to inhibit PP2 (calcineurin), a protein phosphatase which activates immune system T cells, to some extent in the absence of calmodulin.
Product Properties Ki Data binding of [3H]-LTB4 to neutrophil membranes: Ki= 3 μM (pig)
Names and Identifiers Pubchem Sid 488195271 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488195271 IUPAC Name (11E,14E)-icosa-11,14-dienoic acid INCHI InChI=1S/C20H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,21,22)/b7-6+,10-9+ InChi Key XSXIVVZCUAHUJO-AVQMFFATSA-N Canonical SMILES CCCCCC=CCC=CCCCCCCCCCC(=O)O Isomeric SMILES CCCCC/C=C/C/C=C/CCCCCCCCCC(=O)O WGK Germany 3 PubChem CID 5282805 Molecular Weight 308.50
Chemical and Physical Properties Solubility Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml). Insoluble in water. Sensitivity Air sensitive；Light sensitive Refractive Index n20D1.48 Boil Point(°C) 198° C at 0.08 mmHg
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