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Elaiophylin - ≥95%, high purity , CAS No.37318-06-2
Discover Elaiophylin by Aladdin Scientific in ≥95% for only $1,442.90. Available - in Ligands at Aladdin Scientific. Tags: .
Basic Description Synonyms Elaiophylin|37318-06-2|Azalomycin B|Gopalamicin|Antibiotic 5001B|Azalomycin-B|Antibiotic 56-62|Salbomycin|Efomycin E|1CAF8865TM|(3E,5E,7S,8S,11E,13E,15S,16S)-8,16-bis((2S,3R,4S)-4-((2R,4R,5R,6R)-4-(((2R,4S,5S,6S)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran- Specifications & Purity ≥95% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively. A macrolide antibiotic with immunosuppresive activity.
Names and Identifiers IUPAC Name (3E,5E,7S,8S,11E,13E,15S,16S)-8,16-bis[(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-ethyl-2-hydroxy-6-methyloxan-2-yl]-3-hydroxypentan-2-yl]-7,15-dimethyl-1,9-dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione INCHI InChI=1S/C54H88O18/c1-13-37-33(9)71-53(63,25-41(37)67-45-23-39(55)49(61)35(11)65-45)31(7)47(59)29(5)51-27(3)19-15-17-22-44(58)70-52(28(4)20-16-18-21-43(57)69-51)30(6)48(60)32(8)54(64)26-42(38(14-2)34(10)72-54)68-46-24-40(56)50(62)36(12)66-46/h15-22,27-42,45-52,55-56,59-64H,13-14,23-26H2,1-12H3/b19-15+,20-16+,21-18+,22-17+/t27-,28-,29-,30-,31-,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42+,45-,46-,47+,48+,49+,50+,51-,52-,53+,54+/m0/s1 InChi Key OSERMIPXNLXAPD-MJMYBOKFSA-N Canonical SMILES CCC1C(OC(CC1OC2CC(C(C(O2)C)O)O)(C(C)C(C(C)C3C(C=CC=CC(=O)OC(C(C=CC=CC(=O)O3)C)C(C)C(C(C)C4(CC(C(C(O4)C)CC)OC5CC(C(C(O5)C)O)O)O)O)C)O)O)C Isomeric SMILES CC[C@H]1[C@@H](C[C@](O[C@@H]1C)(O)[C@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C=C/C=C/[C@@H]([C@H](OC(=O)/C=C/C=C/[C@@H]2C)[C@H]([C@@H](O)[C@@H]([C@@]3(O[C@@H]([C@H]([C@@H](C3)O[C@@H]4O[C@H]([C@H]([C@H](C4)O)O)C)CC)C)O)C)C)C)C)C)O[C@@H]5O[C@H]([C@H]([C@H](C5)O)O)C PubChem CID 6444206 Molecular Weight 1025.27
Chemical and Physical Properties Solubility Soluble in ethanol (5 mg/ml at 25 °C), methanol, DMF, DMSO (49 mg/ml at 25 °C), and water (<1 mg/ml at 25 °C).
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