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Nuclear Receptors
Vitamin D receptor-like receptors
Eldecalcitol - ≥95%, high purity , Vitamin D receptor agonist, CAS No.104121-92-8, Vitamin D receptor agonist

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Eldecalcitol - ≥95%, high purity , Vitamin D receptor agonist, CAS No.104121-92-8, Vitamin D receptor agonist

Moligand™
≥95%

CAS#: 104121-92-8
Formula: C₃₀H₅₀O₅
Molecular Weight: 490.72
PubChem CID: 6918141

Item Number

E127221

Grouped product items
SKU	Size	Availability	Price	Qty
E127221-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$157.90

View related series

Vitamin D receptor Agonist

Basic Description

Synonyms	Eldecalcitol\|Edirol\|ED-71\|104121-92-8\|2-(3-Hydroxypropoxy)-1,25-dihydroxyvitamin D3\|2-(3-Hydroxypropoxy)calcitriol\|Eldecalcitol [INN:JAN]\|ED 71\|UNII-I2JP8UE90H\|I2JP8UE90H\|(1R,2R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-meth
Specifications & Purity	≥95%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Vitamin D receptor agonist

Product Properties

ALogP	4.3

Associated Targets

VDR Tclin Vitamin D3 receptor 1 Activities

Discover Target: VDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1R,2R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol
INCHI	InChI=1S/C30H50O5/c1-20(9-6-15-29(3,4)34)24-13-14-25-22(10-7-16-30(24,25)5)11-12-23-19-26(32)28(27(33)21(23)2)35-18-8-17-31/h11-12,20,24-28,31-34H,2,6-10,13-19H2,1,3-5H3/b22-11+,23-12-/t20-,24-,25+,26-,27-,28-,30-/m1/s1
InChi Key	FZEXGDDBXLBRTD-AYIMTCTASA-N
Canonical SMILES	CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(C(C(C3=C)O)OCCCO)O)C
Isomeric SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H]([C@H]([C@@H](C3=C)O)OCCCO)O)C
PubChem CID	6918141
Molecular Weight	490.72

Database links

PubChem CID	6918141
CAS Registry No.	104121-92-8
ChEBI	CHEBI:73927
Wikipedia	Eldecalcitol
RCSB PDB Ligand	ED9
DrugCentral Ligand	5169

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	DMSO

References

1. Sanford M, McCormack PL. (2011) Eldecalcitol: a review of its use in the treatment of osteoporosis.. Drugs, 71 (13): (1755-70). [PMID:21902297]
2. Smith SY, Doyle N, Boyer M, Chouinard L, Saito H. (2013) Eldecalcitol, a vitamin D analog, reduces bone turnover and increases trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys.. Bone, 57 (1): (116-22). [PMID:23774444]

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