Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E414078-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $60.90 | |
E414078-2mg | 2mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $90.90 | |
E414078-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $187.90 | |
E414078-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $249.90 | |
E414078-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $652.90 |
BACE Inhibitors
Synonyms | CS-0031645 | AACUJFVOHGRMTR-DPXNYUHVSA-N | 1421852-77-8 | EMAPALUMAB [WHO-DD] | Elenbecestat [INN] | Elenbecestat [USAN] | AKOS040733087 | E2609 | E-2609 | SCHEMBL2620149 | D87146 | E2609E2609 | HY-109055 | N-{3-[(4aS,5R,7aS)-2-Amino-5-methyl-4a,5-dihydro |
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Specifications & Purity | 98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of beta-secretase 1 |
Product Description | Elenbecestat (E2609) is a potent, orally bioavailable and CNS-penetrant BACE-1 inhibitor. Elenbecestat has the potential for Alzheimer's disease (AD) research。 |
ALogP | 1.4 |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-[3-[(4aS,5R,7aS)-2-amino-5-methyl-4,4a,5,7-tetrahydrofuro[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-(difluoromethyl)pyrazine-2-carboxamide |
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INCHI | InChI=1S/C19H18F3N5O2S/c1-9-12-7-30-18(23)27-19(12,8-29-9)11-4-10(2-3-13(11)20)26-17(28)15-6-24-14(5-25-15)16(21)22/h2-6,9,12,16H,7-8H2,1H3,(H2,23,27)(H,26,28)/t9-,12-,19-/m1/s1 |
InChi Key | AACUJFVOHGRMTR-DPXNYUHVSA-N |
Canonical SMILES | CC1C2CSC(=NC2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(N=C4)C(F)F)F)N |
Isomeric SMILES | C[C@@H]1[C@H]2CSC(=N[C@]2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(N=C4)C(F)F)F)N |
Alternate CAS | 1388651-30-6 |
PubChem CID | 57827330 |
Molecular Weight | 437.44 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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B2428396 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428404 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428405 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428409 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428410 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428412 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428413 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428414 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428416 | Certificate of Analysis | Jan 22, 2024 | E414078 |
B2428418 | Certificate of Analysis | Jan 22, 2024 | E414078 |
Solubility | Solubility (25°C) In vitro DMSO: 87 mg/mL (198.88 mM); Ethanol: 11 mg/mL (25.14 mM); Water: Insoluble; |
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