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Elenbecestat - 98%, high purity , CAS No.1388651-30-6, Inhibitor of beta-secretase 1

  • Moligand™
  • ≥98%
Item Number
E414078
Grouped product items
SKUSizeAvailabilityPrice Qty
E414078-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$60.90
E414078-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
E414078-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$187.90
E414078-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
E414078-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$652.90

BACE Inhibitors

View related series
beta-secretase 1 Inhibitor

Basic Description

SynonymsCS-0031645 | AACUJFVOHGRMTR-DPXNYUHVSA-N | 1421852-77-8 | EMAPALUMAB [WHO-DD] | Elenbecestat [INN] | Elenbecestat [USAN] | AKOS040733087 | E2609 | E-2609 | SCHEMBL2620149 | D87146 | E2609E2609 | HY-109055 | N-{3-[(4aS,5R,7aS)-2-Amino-5-methyl-4a,5-dihydro
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of beta-secretase 1
Product Description

Elenbecestat (E2609) is a potent, orally bioavailable and CNS-penetrant BACE-1 inhibitor. Elenbecestat has the potential for Alzheimer's disease (AD) research。

Product Properties

ALogP1.4

Associated Targets

BACE1 Tchem Beta-secretase 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[3-[(4aS,5R,7aS)-2-amino-5-methyl-4,4a,5,7-tetrahydrofuro[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-(difluoromethyl)pyrazine-2-carboxamide
INCHI InChI=1S/C19H18F3N5O2S/c1-9-12-7-30-18(23)27-19(12,8-29-9)11-4-10(2-3-13(11)20)26-17(28)15-6-24-14(5-25-15)16(21)22/h2-6,9,12,16H,7-8H2,1H3,(H2,23,27)(H,26,28)/t9-,12-,19-/m1/s1
InChi Key AACUJFVOHGRMTR-DPXNYUHVSA-N
Canonical SMILES CC1C2CSC(=NC2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(N=C4)C(F)F)F)N
Isomeric SMILES C[C@@H]1[C@H]2CSC(=N[C@]2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(N=C4)C(F)F)F)N
Alternate CAS 1388651-30-6
PubChem CID 57827330
Molecular Weight 437.44

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
B2428396Certificate of AnalysisJan 22, 2024 E414078
B2428404Certificate of AnalysisJan 22, 2024 E414078
B2428405Certificate of AnalysisJan 22, 2024 E414078
B2428409Certificate of AnalysisJan 22, 2024 E414078
B2428410Certificate of AnalysisJan 22, 2024 E414078
B2428412Certificate of AnalysisJan 22, 2024 E414078
B2428413Certificate of AnalysisJan 22, 2024 E414078
B2428414Certificate of AnalysisJan 22, 2024 E414078
B2428416Certificate of AnalysisJan 22, 2024 E414078
B2428418Certificate of AnalysisJan 22, 2024 E414078

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 87 mg/mL (198.88 mM); Ethanol: 11 mg/mL (25.14 mM); Water: Insoluble;

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