Eliglustat hemitartrate - 99%, high purity , CAS No.928659-70-5

Item Number

E413101

Grouped product items
SKU	Size	Availability	Price
E413101-1mg	1mg	In stock	$151.90
E413101-5mg	5mg	In stock	$411.90
E413101-25mg	25mg	In stock	$1,270.90
E413101-100mg	100mg	In stock	$3,089.90

Glucosylceramide Synthase Inhibitors

Basic Description

Synonyms	AC-35333 \| Eliglustat tartrate \| EMD-IT-3456 \| bis(1-((2R,3R)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-hydroxy-2-(octanoylamino)propyl)pyrrolidinium) (2R,3R)-2,3-dihydroxysuccinate \| MFCD20617651 \| O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiofosfa
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information Eliglustat hemitartrate Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM. Targets Glucosylceramide Synthase (Cell-free assay) 24 nM

Names and Identifiers

IUPAC Name	N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide;(2R,3R)-2,3-dihydroxybutanedioic acid
INCHI	InChI=1S/2C23H36N2O4.C4H6O6/c21-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20;5-1(3(7)8)2(6)4(9)10/h210-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26);1-2,5-6H,(H,7,8)(H,9,10)/t2*19-,23-;1-,2-/m111/s1
InChi Key	KUBARPMUNHKBIQ-VTHUDJRQSA-N
Canonical SMILES	CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.C(C(C(=O)O)O)(C(=O)O)O
Isomeric SMILES	CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
PubChem CID	52918379
Molecular Weight	959.17

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
I2207626	Certificate of Analysis	Jul 03, 2022	E413101
I2207627	Certificate of Analysis	Jul 03, 2022	E413101
I2207628	Certificate of Analysis	Jul 03, 2022	E413101
I2207660	Certificate of Analysis	Jul 03, 2022	E413101

Solubility

Solubility (25°C) In vitro DMSO: 100 mg/mL (104.25 mM); Water: 100 mg/mL (104.25 mM); Ethanol: 10 mg/mL (10.42 mM);

Sensitivity

Moisture sensitive

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Basic Description