elzovantinib - ≥98%, high purity , CAS No.2271119-26-5, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase

Item Number

E610109

Grouped product items
SKU	Size	Availability	Price
E610109-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$60.90
E610109-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$147.90
E610109-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$392.90
E610109-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$587.90

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Basic Description

Synonyms	elzovantinib\|TPX-0022\|2271119-26-5\|CSF1R-IN-2\|Elzovantinib [INN]\|TTY12Q00LY\|UNII-TTY12Q00LY\|TPX0022\|Elzovantinib [WHO-DD]\|ELZOVANTINIB [USAN]\|TPX002\|CHEMBL5095061\|SCHEMBL20694441\|GTPL11869\|GLXC-26839\|EX-A5131\|NSC820832\|s9620\|AKOS040740444\|NSC-820832\|compo
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase
Product Description	Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC, MET and c-FMS, with IC50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively.

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(11S)-16-amino-2-ethyl-6-fluoro-11-methyl-14-oxo-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaene-5-carbonitrile
INCHI	InChI=1S/C20H20FN7O2/c1-3-27-10-13-12(8-22)14(21)4-5-15(13)30-11(2)9-24-20(29)17-18(23)26-28-7-6-16(27)25-19(17)28/h4-7,11H,3,9-10H2,1-2H3,(H2,23,26)(H,24,29)/t11-/m0/s1
InChi Key	UUDPUQDMSHQSKH-NSHDSACASA-N
Canonical SMILES	CCN1CC2=C(C=CC(=C2C#N)F)OC(CNC(=O)C3=C4N=C1C=CN4N=C3N)C
Isomeric SMILES	CCN1CC2=C(C=CC(=C2C#N)F)O[C@H](CNC(=O)C3=C4N=C1C=CN4N=C3N)C
Alternate CAS	2271119-26-5
PubChem CID	137455315
Molecular Weight	409.42

CAS Registry No.

PubChem CID

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Basic Description