EMAC10101d is a potent and selective toward hCA II inhibitor, with a K i of 8.1 nM.
In Vitro
EMAC10101d exhibits K i values of 9627.4 nM, 8.1 nM, 224.6 nM and 154.9 nM for hCA Ⅰ, hCA II, hCAⅨ and hCA Ⅻ, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.