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Engeletin - ≥98%, high purity , CAS No.572-31-6

  • ≥98%
Item Number
E414350
Grouped product items
SKUSizeAvailabilityPrice Qty
E414350-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$13.90
E414350-5mg
5mg
In stock
$39.90
E414350-25mg
25mg
In stock
$145.90
E414350-50mg
50mg
In stock
$235.90
E414350-100mg
100mg
In stock
$399.90

NF-κB Inhibitors

View related series
Flavonoids Natural glycosides

Basic Description

SynonymsEngeletin|572-31-6|Engelitin|3-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one (2R-trans)-|4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxypheny
Specifications & Purity≥98%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Information

Engeletin Engeletin (Dihydrokaempferol 3-rhamnoside), a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. engeletin againsts LPS-stimulated endometritis in mice via negative regulation of pro-inflammatory mediators via the TLR4-regulated NF-κB pathway .


Targets

NF-κB

Names and Identifiers

IUPAC Name (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one
INCHI InChI=1S/C21H22O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-25,27-28H,1H3/t8-,15-,17+,18+,19+,20-,21-/m0/s1
InChi Key VQUPQWGKORWZII-WDPYGAQVSA-N
Canonical SMILES CC1C(C(C(C(O1)OC2C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O
Isomeric SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O
PubChem CID 6453452
Molecular Weight 434.4

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
H2409468Certificate of AnalysisJul 19, 2024 E414350
H2409469Certificate of AnalysisJul 19, 2024 E414350
H2409470Certificate of AnalysisJul 19, 2024 E414350
H2409471Certificate of AnalysisJul 19, 2024 E414350
I2220388Certificate of AnalysisJul 07, 2022 E414350
I2220389Certificate of AnalysisJul 07, 2022 E414350
I2220390Certificate of AnalysisJul 07, 2022 E414350
I2220391Certificate of AnalysisJul 07, 2022 E414350

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 86 mg/mL (197.97 mM);DMSO: 2 mg/mL, clear
SensitivityAir sensitive;Heat sensitive

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Solution Calculators