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EP1013 - 10mM in DMSO, high purity , CAS No.223568-55-6(DMSO)

  • 10mM in DMSO
Item Number
E654834
Grouped product items
SKUSizeAvailabilityPrice Qty
E654834-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$222.90
View related series
Apoptosis Caspase

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes

In Vivo

EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal\nrate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Caspase

Names and Identifiers

Canonical SMILES CC(C)C(C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
Molecular Weight 382.38

Certificates

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