| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| E655874-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $211.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Desiccated,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research In Vitro Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Anaerobes isolates Concentration: 0-32 μg/mL Incubation Time: Result: Showed MIC 50 /MIC 90 for all anaerobes isolates tested of 2 and 4 μg/mL, respectively. IC50& Target:IC 50 : 0.31 μM (LeuRS) |
| Canonical SMILES | B1(C2=C(C=CC=C2OCCCO)C(O1)CN)O.Cl |
|---|---|
| Molecular Weight | 273.52 |
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