Etomoxir - ≥98 %, high purity , CAS No.124083-20-1

Item Number

E124862

• Synonyms: ETOMOXIR [WHO-DD] | HY-50202 | STK709190 | DTXSID801025772 | Etomoxir [INN] | AC-32627 | (R)-(+)-Etomoxir | 2-OXIRANECARBOXYLIC ACID, 2-(6-(4-CHLOROPHENOXY)HEXYL)-, ETHYL ESTER, (2R)- | CHEBI:95011 | NCGC00378789-04 | BDBM50237625 | UNII-MSB3DD2XP6 | GTPL
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: An inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oxidation of long-chain acyl CoA esters. Also a strong inhibitor of mitochondrial CPT1 and a candidate as an anti-diabetic drug.CPT1 inhibitor. Inhibits β-oxidation in mito
• Storage Temp: Protected from light,Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Etomoxir is a cell-permeable, irreversible, and stereospecific inhibitor of carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 μM and 40 μM, respectively.