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ETP-46464 - 98%, high purity , CAS No.1345675-02-6

  • ≥98%
Item Number
E125288
Grouped product items
SKUSizeAvailabilityPrice Qty
E125288-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
E125288-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
E125288-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
E125288-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$439.90
E125288-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90
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Cell Cycle/DNA Damage mTOR ATM/ATR

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsETP-46464 is a potent and selective inhibitor of the DNA damage response kinase Ataxia telangiectasia-mutated (ATM) - and Rad3-related (ATR) with an IC50 of 25 nM. ETP-46464 shows moderate activity against PI3K and is a potent inhibitor of mTor, but is se
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets

PRKDC Tchem DNA-dependent protein kinase catalytic subunit 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATR Tchem Serine/threonine-protein kinase ATR 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATM Tchem Serine-protein kinase ATM 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MTOR Tclin Serine/threonine-protein kinase mTOR 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-methyl-2-[4-(2-oxo-9-quinolin-3-yl-4H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl]propanenitrile
INCHI InChI=1S/C30H22N4O2/c1-30(2,18-31)23-8-10-24(11-9-23)34-28-22(17-36-29(34)35)16-33-27-12-7-19(14-25(27)28)21-13-20-5-3-4-6-26(20)32-15-21/h3-16H,17H2,1-2H3
InChi Key DPLMXAYKJZOTKO-UHFFFAOYSA-N
Canonical SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
Isomeric SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
PubChem CID 72199292
Molecular Weight 470.52

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO 6 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. ETP-46464 - 10mM in DMSO, used for , CAS No. 1345675-02-6, by Aladdin Scientific
    ETP-46464

    Starting at $79.90

Solution Calculators

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