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Etravirine (TMC125) - ≥95%, high purity , CAS No.269055-15-4
Basic Description
| Synonyms | Etravirine|269055-15-4|Intelence|TMC125|TMC-125|Etravirine (TMC125)|TMC 125|R165335|R-165335|4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile|TMC125 cpd|4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY |
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| Specifications & Purity | ≥95% |
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| Biochemical and Physiological Mechanisms |
Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection. |
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| Storage Temp | Store at -20°C,Argon charged |
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| Shipped In | Ice chest + Ice pads |
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Names and Identifiers
| Pubchem Sid | 488188569 |
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| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488188569 |
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| IUPAC Name | 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile |
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| INCHI | InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27) |
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| InChi Key | PYGWGZALEOIKDF-UHFFFAOYSA-N |
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| Canonical SMILES | CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N |
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| Isomeric SMILES | CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N |
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| PubChem CID | 193962 |
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| Molecular Weight | 435.28 |
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Chemical and Physical Properties
| Solubility | DMSO 42 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
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| Sensitivity | Air sensitive，Heat sensitive ，Light sensitive |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
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| Hazard Statements | H413:May cause long lasting harmful effects to aquatic life H302:Harmful if swallowed |
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| Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
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