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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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E650179-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $276.90 | |
E650179-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $580.90 | |
E650179-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $980.90 |
Phenols Monophenols
Synonyms | Euparin|532-48-9|Euparine|1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone|46YA021ENM|CHEBI:67437|1-(6-Hydroxy-2-(1-methylethenyl)-5-benzofuranyl)ethanone|Ethanone, 1-[6-hydroxy-2-(1-methylethenyl)-5-benzofuranyl]-|UNII-46YA021ENM|Ethanone, 1-(6-h |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects. |
Storage Temp | Protected from light,Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Product Description | Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects. In Vitro In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC 50 values of 0.47 µg/mL, 0.12 µg/mL, and 0.15 µg/mL, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
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IUPAC Name | 1-(6-hydroxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone |
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INCHI | InChI=1S/C13H12O3/c1-7(2)12-5-9-4-10(8(3)14)11(15)6-13(9)16-12/h4-6,15H,1H2,2-3H3 |
InChi Key | OPUFDNZTKHPZHM-UHFFFAOYSA-N |
Canonical SMILES | CC(=C)C1=CC2=CC(=C(C=C2O1)O)C(=O)C |
Isomeric SMILES | CC(=C)C1=CC2=CC(=C(C=C2O1)O)C(=O)C |
Alternate CAS | 532-48-9 |
PubChem CID | 119039 |
MeSH Entry Terms | euparin |
Molecular Weight | 216.23 |
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