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FABP4 Mouse mAb - Primary antibody, specific to FABP4, Mouse IgG1

  • Azide Free
  • Carrier Free
  • ExactAb™
  • High performance
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (C12); Mouse anti Human FABP4 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Pig,Rat
  • Isotype: Mouse IgG1
    Application:
  • IHC
  • WB
Item Number
Ab102606
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab102606-10μl
10μl
In stock
$59.90
Ab102606-20μl
20μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab102606-50μl
50μl
In stock
$179.90
Ab102606-100μl
100μl
In stock
$279.90
Ab102606-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

mAb (C12); Mouse anti Human FABP4 Antibody; WB, IHC; Unconjugated

View related series
Accession#:P15090 FABP4 Gene ID:2167

Basic Description

Product NameFABP4 Mouse mAb - Primary antibody, specific to FABP4, Mouse IgG1
Synonyms3T3-L1 lipid-binding protein antibody; 422/aP2 antibody; A-FABP antibody; adipocyte antibody; Adipocyte lipid binding protein antibody; Adipocyte lipid-binding protein antibody; Adipocyte protein AP2 antibody; Adipocyte-type fatty acid-binding protein ant
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot
Host speciesMouse
SpecificityFABP4
ImmunogenRecombinant FABP4 expressed in E.coli (AA 2-132)
Positive ControlWB: Mouse heart, Mouse skeletal muscle tissue lysates and HUVEC cell lysate. IHC: Human and Porcine cardiac muscle tissues.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, High performance, Validated
Product Description

Mouse anti Human FABP4 Antibody, Monoclonal (C12), could be used for WB, IHC and so on. Application WB: 0.01-2 µg/mL IHC: 5-20 μg/mL

Protein Function

Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A + Protein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

FABP4 Mouse mAb (Ab102606) - Western Blot
All lanes: FABP4 Mouse mAb (Ab102606) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/40000 dilution

Predicted band size: 15 kDa
Observed band size: 14 kDa
Exposure time: 0.9 s


FABP4 Mouse mAb (Ab102606) - Western Blot
All lanes: FABP4 Mouse mAb (Ab102606) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 15 kDa
Observed band size: 14 kDa
Exposure time: 159.3 s

FABP4 Mouse mAb (Ab102606) - IHC
DAB staining on IHC
Sample: Porcine Cardiac Muscle Tissue
Primary Ab: 10 µg /mL FABP4 Mouse mAb (Ab102606)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

FABP4 Mouse mAb (Ab102606) - IHC
DAB staining on IHC
Sample: Human Cardiac Muscle Tissue
Primary Ab: 10 µg/mL FABP4 Mouse mAb (Ab102606)
Control: Used PBS instead of primary antibody
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

Associated Targets

FABP4 Tchem Fatty acid-binding protein, adipocyte 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

5-20 µg/mL

WB

0.01-2 µg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102397Certificate of AnalysisJan 10, 2024 Ab102606
ZJ24F0102396Certificate of AnalysisJan 10, 2024 Ab102606
ZJ24F0102395Certificate of AnalysisJan 10, 2024 Ab102606

Related Documents

References

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2. Liu X, Huang X, Lin W, Wang D, Diao Y, Li H, Hui X, Wang Y, Xu A, Wu D et al..  (2011)  New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein..  Bioorg Med Chem Lett,  21  (10): (2949-52).  [PMID:21481589]
3. Oddi S, Scipioni L, Totaro A, Angelucci C, Dufrusine B, Sabatucci A, Tortolani D, Coletta I, Alisi MA, Polenzani L et al..  (2019)  The anti-inflammatory agent bindarit acts as a modulator of fatty acid-binding protein 4 in human monocytic cells..  Sci Rep,  (1): (15155).  [PMID:31641194]
4. Haiyan Cai,Guirui Yan,Xiaodong Zhang,Olena Gorbenko,Heyao Wang,Weiliang Zhu.  (2010-05-18)  Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening..  Bioorganic & medicinal chemistry letters,  20  ((12)): (3675-3679).  [PMID:20471252]
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10. Gao DD, Dou HX, Su HX, Zhang MM, Wang T, Liu QF, Cai HY, Ding HP, Yang Z, Zhu WL, Xu YC, Wang HY, Li YX..  (2018)  From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4..  Eur J Med Chem,  154  (44-59).  [PMID:29775936]
11. Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Wang L, Bogdan DM, Falcone J, Smietalo N, Zhou Y, Ralph B, Hsu HC, Li H, Rizzo RC, Deutsch DG, Kaczocha M, Ojima I..  (2018)  SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins..  Eur J Med Chem,  154  (233-252).  [PMID:29803996]
12. He Y, Dou H, Gao D, Wang T, Zhang M, Wang H, Li Y..  (2019)  Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor..  Bioorg Med Chem,  27  (19): (115015-115015).  [PMID:31420256]
13. Oukoloff K, Lucero B, Francisco KR, Brunden KR, Ballatore C..  (2019)  1,2,4-Triazolo[1,5-a]pyrimidines in drug design..  Eur J Med Chem,  165  (332-346).  [PMID:30703745]
14. Baxa, C A CA and 7 more authors..  (1989)  Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA..  Biochemistry,    (31):   [PMID:2481498]
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