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FABP5-IN-1 - 10mM in DMSO, high purity , CAS No.2132990-98-6(DMSO)

  • 10mM in DMSO
Item Number
F654997
Grouped product items
SKUSizeAvailabilityPrice Qty
F654997-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$528.90
View related series
FABP Metabolic Enzyme/Protease

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

FABP5-IN-1 is a selective and high affinity fatty acid binding protein 5 (FABP5) inhibitor with a K i value of 1.7 μM, and does not bind to both FABP3 and FABP7. FABP5-IN-1 shows potent antinociceptive effects

In Vivo

FABP5-IN-1 (Compounds 4j; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice injected with complete Freund’s adjuvant (CFA) Dosage: 20 mg/kg Administration: Intraperitoneal injection; for 90 minutes Result: Displayed potent antinociceptive effects in CFA model.

IC50& Target:Ki: 1.7 μM (FABP5)

Names and Identifiers

Canonical SMILES O=C(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)[C@H]4[C@@H](C5=CC=CC=C5OC)[C@H](C(O)=O)[C@@H]4C6=CC=CC=C6OC
Molecular Weight 534.60

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