FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.
Appearance:Solid
IC50& Target:K D : 20 nM (FABP7), 874 nM (FABP5)
In Vitro:FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury. MCE has not independently confirmed th
In Vivo:MF 6 (1mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response. MCE has not independently confirmed the accuracy of these methods. They ar
Biological Activity:FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with K D values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.
