A bridge to protein science——Aladdin@Polypeptide

Product Manager：

Harrison Michael

Important peptide synthesis

Peptide synthesis is a basic technique for peptide synthesis in biochemistry and molecular biology. It usually involves chemically linking amino acids in a specific order to create a desired peptide sequence. Peptide is a key molecule, which is a compound formed by dehydration and condensation of less than 100 amino acids with a molecular structure between amino acids and proteins and has high biological activity. Peptides play crucial roles in a variety of biological processes and are of great significance in drug development, structural biology and other research fields.

A wide range of research needs

Peptide synthesis reagents play a crucial role in a variety of scientific experiments in multiple disciplines, and promote the research of drug discovery, structural biology, immunology, cell biology, proteomics and so on.

Drug development: Peptide synthesis reagents are widely used in the development of peptide drugs. Peptide drugs have attracted attention due to their high specificity and low toxicity compared with traditional small molecule drugs. Researchers design and synthesize peptides to target specific proteins associated with diseases such as cancer, diabetes, and autoimmune diseases.

Structural biology: Peptides are valuable tools for studying protein structure and function. Peptide synthesis reagents enable the production of peptide fragments that can be used in techniques such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy to determine protein structures at atomic resolution. By synthesizing peptides that correspond to specific regions of a protein, researchers can probe its structure as well as its interactions with other molecules.

Immunology: Peptides are used in immunological studies to study antigen-antibody interactions and to develop vaccines. Peptide synthesis reagents are used to produce antigenic peptides that can be used to enhance antibodies against specific proteins or pathogens. Peptide-based vaccines are being investigated for their potential to induce immune responses against infectious diseases and cancer.

Cell biology and Molecular genetics: Peptides synthesized with specific reagents are used in cell biology experiments to study signaling pathways, protein interactions, and cellular processes. For example, cell-penetrating peptides (CPPs) synthesized with appropriate reagents are used to deliver biomolecules such as proteins, nucleic acids or drugs into cells for research or therapy. In addition, peptides are used as molecular probes to label specific cellular structures or proteins for visualization using fluorescence microscopy techniques.

Proteomics and biomarker discovery: Peptide synthesis reagents are indispensable for proteomics studies aimed at the identification and quantification of proteins present in biological samples. Researchers used synthetic peptides as a mass spectrometric based proteomics standard in order to accurately quantify protein abundance. Peptide libraries synthesized with different sequences have also been used in biomarker discovery to identify peptides associated with specific diseases or physiological conditions.

Chemical biology and drug screening: Peptides are synthesized with specialized reagents for chemical biology studies and drug screening tests. Researchers design and synthesize peptide libraries containing different sequences to screen for peptides with desired biological activities, such as enzyme inhibition, receptor binding, or antimicrobial properties. These peptides can be used as lead compounds for the development of novel therapeutic agents or chemical probes for studying biological processes.

Welcom to visit our website for more details and to view our comprehensive product line of peptide synthesis reagents and biochemical reagents.

Aladdin：https://www.aladdinsci.com/