Benzophenone

Product Manager：Nick Wilde

Benzophenone is the organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO. It is a white solid that is soluble in organic solvents. Benzophenone is a widely used building block in organic chemistry, being the parent diarylketone.

Application

Benzophenone can be used as a photo initiator in ultraviolet(UV)-curing applications such as inks, imaging, and clear coatings in the printing industry. Benzophenone prevents UV light from damaging scents and colors in products such as perfumes and soaps.

Benzophenone can also be added to plastic packaging as a UV blocker to prevent photo-degradation of the packaging polymers or its contents. Its use allows manufacturers to package the product in clear glass or plastic (such as a PETE water bottle). Without it, opaque or dark packaging would be required.

In biological applications, benzophenones have been used extensively as photophysical probes to identify and map peptide–protein interactions.

Benzophenone is used as an additive in flavorings or perfumes for "sweet-woody-geranium-like notes."

Recent Literature

A transition metal-free one-pot reaction of secondary alcohols and 2-aminoalcohols provides various substituted NH-pyrroles via an Oppenauer oxidation in the presence of benzophenone as an inexpensive reagent. The oxidation of the secondary alcohols under mild condition to ketones is followed by an in situ condensation with aminoalcohol, and oxidative cyclization to the target pyrrole ring.

J.-A. Shin, J. Kim, H. Lee, S. Ha, H.-Y. Lee, J. Org. Chem., 2019, 84, 4558-4565.

https://doi.org/10.1021/acs.joc.8b03215

Quoted from: https://en.wikipedia.org/wiki/Benzophenone

https://www.organic-chemistry.org/chemicals/oxidations/benzophenone.shtm

Aladdin：https://www.aladdinsci.com