Fenobam - 98%, high purity , CAS No.57653-26-6, Allosteric modulator of mGlu 5 receptor

Item Number

F274825

Grouped product items
SKU	Size	Availability	Price
F274825-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$39.90
F274825-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$89.90
F274825-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$206.90
F274825-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$260.90
F274825-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$931.90
F274825-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$619.90

mGlu 5 antagonist

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Basic Description

Synonyms	MLS006011708 \| [3H]fenobam \| LP00842 \| GTPL1433 \| DWPQODZAOSWNHB-UHFFFAOYSA-N \| Fenobam \| NCGC00092384-04 \| FT-0630701 \| 1-m-chlorophenyl-3-(1-methyl-4-oxo-2-imidazolidinylidene)urea \| Q5443558 \| 1-(3-chlorophenyl)-3-[(2Z)-1-methyl-4-oxoimidazolidin-2-yli
Specifications & Purity	98%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of mGlu 5 receptor
Product Description	Fenobam is a selective, orally active, and brain-penetrant mGluR5 antagonist acting at an allosteric modulatory site (Kds of 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively). Fenobam displays inverse agonist activity which blocks the mGlu5 receptor basal activity with an IC50 of 84 nM. Fenobam exerts anxiolytic activity。

Names and Identifiers

IUPAC Name	1-(3-chlorophenyl)-3-(1-methyl-4-oxoimidazolidin-2-ylidene)urea
INCHI	InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)
InChi Key	DWPQODZAOSWNHB-UHFFFAOYSA-N
Canonical SMILES	CN1CC(=O)NC1=NC(=O)NC2=CC(=CC=C2)Cl
Isomeric SMILES	CN1CC(=O)NC1=NC(=O)NC2=CC(=CC=C2)Cl
Alternate CAS	57653-26-6
PubChem CID	135497698
MeSH Entry Terms	fenobam;fenobam anhydrous;fenobam monohydrate
Molecular Weight	266.68

Certificates

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12 results found

Lot Number	Certificate Type	Date	Item
B2423428	Certificate of Analysis	Jan 12, 2024	F274825
B2423429	Certificate of Analysis	Jan 12, 2024	F274825
B2423430	Certificate of Analysis	Jan 12, 2024	F274825
B2423431	Certificate of Analysis	Jan 12, 2024	F274825
B2423432	Certificate of Analysis	Jan 12, 2024	F274825
B2423433	Certificate of Analysis	Jan 12, 2024	F274825
B2423434	Certificate of Analysis	Jan 12, 2024	F274825
B2423471	Certificate of Analysis	Jan 12, 2024	F274825
B2423472	Certificate of Analysis	Jan 12, 2024	F274825
B2423473	Certificate of Analysis	Jan 12, 2024	F274825
B2423477	Certificate of Analysis	Jan 12, 2024	F274825
B2423481	Certificate of Analysis	Jan 12, 2024	F274825

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H300:Fatal if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.

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Basic Description