Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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pAb; Rabbit anti Human FKBP52 Antibody; WB, IHC; Unconjugated
SKU | Size | Availability | Price | Qty |
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Ab103696-10μl | 10μl | In stock | $66.90 | |
Ab103696-20μl | 20μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $99.90 | |
Ab103696-50μl | 50μl | In stock | $199.90 | |
Ab103696-100μl | 100μl | In stock | $289.90 | |
Ab103696-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
pAb; Rabbit anti Human FKBP52 Antibody; WB, IHC; Unconjugated
Product Name | FKBP52 Antibody - Primary antibody, specific to FKBP52, Rabbit IgG |
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Synonyms | 51 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; EC 5.2.1.8; FK506 binding protein 4, 59kDa; FK506-binding protein 4 (59kD); FK506-binding protein 4; FKBP4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52T-cell FK506-binding protein, 59kD; FKBP59; |
Specifications & Purity | ExactAb™, Validated, Carrier Free, High performance, Lot by Lot |
Host species | Rabbit |
Specificity | FKBP52 |
Immunogen | Recombinant FKBP4 expressed in E.coli (AA 2-459). |
Positive Control | WB: Recombinant Human FKBP4; K562, Porcine cerebrum and Porcine kidney lysates. IHC: Human stomach, prostate cancer, cerebrum, colorectal cancer, liver and lung cancer tissues. |
Conjugation | Unconjugated |
Grade | Carrier Free, ExactAb™, High performance, Validated |
Product Description | Rabbit anti Human FKBP52 Antibody, Polyclonal, could be used for WB, IHC and so on. |
Isotype | Rabbit IgG |
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SDS-PAGE | 150 kDa |
Purification Method | Antigen affinity purified + Protein A purified |
Form | Liquid |
Concentration | Lot by Lot |
Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Shipped In | Ice chest + Ice pads |
Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Application | Dilution info |
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IHC | 5-30 µg/mL |
WB | 0.01-3 µg/mL |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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ZJ24F0505952 | Certificate of Analysis | May 22, 2024 | Ab103696 |
ZJ24F0505953 | Certificate of Analysis | May 22, 2024 | Ab103696 |
ZJ24F0505954 | Certificate of Analysis | May 22, 2024 | Ab103696 |
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7. Zhao L, Huang W, Liu H, Wang L, Zhong W, Xiao J, Hu Y, Li S.. (2006) FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates.. J Med Chem, 49 (14): (4059-4071). [PMID:16821768] |
8. Zhao L, Liu H, Wang L, Li S.. (2006) Modeling and synthesis of non-cyclic derivatives of GPI-1046 as potential FKBP ligands with neurotrophic properties.. Bioorg Med Chem Lett, 16 (16): (4385-4390). [PMID:16753298] |
9. Gopalakrishnan R, Kozany C, Gaali S, Kress C, Hoogeland B, Bracher A, Hausch F.. (2012) Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52.. J Med Chem, 55 (9): (4114-4122). [PMID:22455444] |
10. Feng X, Sippel C, Knaup FH, Bracher A, Staibano S, Romano MF, Hausch F.. (2020) A Novel Decalin-Based Bicyclic Scaffold for FKBP51-Selective Ligands.. J Med Chem, 63 (1): (231-240). [PMID:31800244] |
11. de la Sierra-Gallay IL, Belnou M, Chambraud B, Genet M, van Tilbeurgh H, Aumont-Nicaise M, Desmadril M, Baulieu EE, Jacquot Y, Byrne C.. (2020) Bioinspired Hybrid Fluorescent Ligands for the FK1 Domain of FKBP52.. J Med Chem, 63 (18): (10330-10338). [PMID:32866001] |
12. Bauder M, Meyners C, Purder PL, Merz S, Sugiarto WO, Voll AM, Heymann T, Hausch F.. (2021) Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors.. J Med Chem, 64 (6.0): (3320-3349). [PMID:33666419] |
13. Peattie, D A DA and 6 more authors.. (1992) Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:1279700] |
14. Yem, A W AW and 6 more authors.. (1992) The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13.. The Journal of biological chemistry, (15): [PMID:1371107] |
15. Tai, P K PK, Albers, M W MW, Chang, H H, Faber, L E LE and Schreiber, S L SL.. (1992) Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex.. Science (New York, N.Y.), (29): [PMID:1376003] |
16. Wiederrecht, G G and 9 more authors.. (1992) Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex.. The Journal of biological chemistry, (25): [PMID:1383226] |
17. Sanchez, E R ER, Faber, L E LE, Henzel, W J WJ and Pratt, W B WB.. (1990) The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins.. Biochemistry, (29): [PMID:2378870] |
18. Guo, Y Y and 7 more authors.. (2001) Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex.. The Journal of biological chemistry, (7): [PMID:11583998] |
19. Krummrei, Ulrike U, Baulieu, Etienne-Emile EE and Chambraud, Béatrice B.. (2003) The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis.. Proceedings of the National Academy of Sciences of the United States of America, (4): [PMID:12604780] |
20. Wu, Beili B and 9 more authors.. (2004) 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.. Proceedings of the National Academy of Sciences of the United States of America, (1): [PMID:15159550] |
21. Scherer, Steven E SE and 216 more authors.. (2006) The finished DNA sequence of human chromosome 12.. Nature, (16): [PMID:16541075] |
22. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP.. (2006) A probability-based approach for high-throughput protein phosphorylation analysis and site localization.. Nature biotechnology, [PMID:16964243] |
23. Matsuoka, Shuhei S and 12 more authors.. (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.. Science (New York, N.Y.), (25): [PMID:17525332] |
24. Dephoure, Noah N and 6 more authors.. (2008) A quantitative atlas of mitotic phosphorylation.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:18669648] |
25. Shim, Sangwoo S and 9 more authors.. (2009) Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.. Neuron, (25): [PMID:19945390] |
26. Shimamoto, Seiko S, Kubota, Yasuo Y, Tokumitsu, Hiroshi H and Kobayashi, Ryoji R.. (2010) S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats.. FEBS letters, (19): [PMID:20188096] |
27. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
28. Gallo, Luciana I LI, Lagadari, Mariana M, Piwien-Pilipuk, Graciela G and Galigniana, Mario D MD.. (2011) The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.. The Journal of biological chemistry, (26): [PMID:21730050] |
29. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |