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Flavin adenine dinucleotide disodium salt hydrate - for cell culture,>95%, high purity , CAS No.84366-81-4

3 Citations

for cell culture

≥95%

CAS#: 84366-81-4
Formula: C₂₇H₃₁N₉Na₂O₁₅P₂·xH₂O
Molecular Weight: 829.51 (anhydrous basis)
Beilstein Registry Number: 5326842
EC Number: 282-733-8
MDL number: MFCD08277021
PubChem CID: 2734019

Item Number

F100990

Grouped product items
SKU	Size	Availability	Price
F100990-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$131.90
F100990-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$219.90
F100990-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$383.90

Redox cofactor of flavoproteins

Basic Description

Synonyms	FAD-Na2 \| NCGC00167573-01 \| Flavin adenine dinucleotide disodium \| FLAVINE ADENINE DINUCLEOTIDE DISODIUM \| DTXCID8026723 \| DTXSID0046723 \| Tox21_112566 \| DISODIUM FLAVINE ADENINE DINUCLEOTIDE \| FAD sodium salt \| CAS-84366-81-4 \| UNII-67U7UHJ04C \| FLAVIN A
Specifications & Purity	for cell culture, ≥95%
Biochemical and Physiological Mechanisms	Redox cofactor of flavoproteins. Flavin adenine dinucleotide is a component of pyruvate dehydrogenase complex. Role in nitric oxide synthesis. Active in vitro .
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	for cell culture
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Product Introduction Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b5 reductase enzyme. With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH2. Application Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction. It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice. Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

Names and Identifiers

IUPAC Name	disodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] phosphate
INCHI	InChI=1S/C27H33N9O15P2.2Na/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;/q;2*+1/p-2/t14-,15+,16+,19-,20+,21+,26+;;/m0../s1
InChi Key	XLRHXNIVIZZOON-WFUPGROFSA-L
Canonical SMILES	CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)([O-])OP(=O)([O-])OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O.[Na+].[Na+]
Isomeric SMILES	CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)([O-])OP(=O)([O-])OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O.[Na+].[Na+]
WGK Germany	3
RTECS	AU7470000
PubChem CID	2734019
Molecular Weight	829.51 (anhydrous basis)
Beilstein	5326842
Reaxy-Rn	5326842

Certificates

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11 results found

Lot Number	Certificate Type	Date	Item
H2414496	Certificate of Analysis	Jul 18, 2024	F100990
H2414497	Certificate of Analysis	Jul 18, 2024	F100990
H2414498	Certificate of Analysis	Jul 18, 2024	F100990
H2414499	Certificate of Analysis	Jul 18, 2024	F100990
H2414576	Certificate of Analysis	Jul 18, 2024	F100990
I2320557	Certificate of Analysis	Sep 11, 2023	F100990
I2320558	Certificate of Analysis	Sep 11, 2023	F100990
I2320559	Certificate of Analysis	Sep 11, 2023	F100990
F2330701	Certificate of Analysis	Feb 06, 2023	F100990
K2211476	Certificate of Analysis	Aug 19, 2022	F100990
K2211505	Certificate of Analysis	Aug 19, 2022	F100990

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Sensitivity

Light&Moisture&Heat sensitive

Specific Rotation[α]

-30.0 to -25.0 deg(C=1, H2O)

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
WGK Germany	3
RTECS	AU7470000
Reaxy-Rn	5326842
Merck Index	4091

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jianfeng Zhang, Wenrong Bing, Tiancheng Hu, Xu Zhou, Jiejing Zhang, Jing Liang, Yongguang Li. (2023) Enhanced biodegradation of phenol by microbial collaboration: Resistance, metabolite utilization, and pH stabilization. ENVIRONMENTAL RESEARCH, 238 (11): (117269). [PMID:37776942] [10.1016/j.envres.2023.117269]
2. Hao Fei, Xie Xing, Feng Zhixin, Chen Rong, Wei Yanna, Liu Jin, Xiong Qiyan, Shao Guoqing, Lin Johnson. (2022) NADH oxidase of Mycoplasma hyopneumoniae functions as a potential mediator of virulence. BMC Veterinary Research, 18 (1): (1-14). [PMID:35366872] [10.1186/s12917-022-03230-7]
3. Lijun Geng, Xudong Yu, Yajuan Li, Yanqiu Wang, Yongquan Wu, Jujie Ren, Fengfeng Xue, Tao Yi. (2019) Instant hydrogel formation of terpyridine-based complexes triggered by DNA via non-covalent interaction. Nanoscale, 11 (9): (4044-4052). [PMID:30768104] [10.1039/C8NR08532C]

References

1. Jianfeng Zhang, Wenrong Bing, Tiancheng Hu, Xu Zhou, Jiejing Zhang, Jing Liang, Yongguang Li. (2023) Enhanced biodegradation of phenol by microbial collaboration: Resistance, metabolite utilization, and pH stabilization. ENVIRONMENTAL RESEARCH, 238 (11): (117269). [PMID:37776942] [10.1016/j.envres.2023.117269]
2. Hao Fei, Xie Xing, Feng Zhixin, Chen Rong, Wei Yanna, Liu Jin, Xiong Qiyan, Shao Guoqing, Lin Johnson. (2022) NADH oxidase of Mycoplasma hyopneumoniae functions as a potential mediator of virulence. BMC Veterinary Research, 18 (1): (1-14). [PMID:35366872] [10.1186/s12917-022-03230-7]
3. Lijun Geng, Xudong Yu, Yajuan Li, Yanqiu Wang, Yongquan Wu, Jujie Ren, Fengfeng Xue, Tao Yi. (2019) Instant hydrogel formation of terpyridine-based complexes triggered by DNA via non-covalent interaction. Nanoscale, 11 (9): (4044-4052). [PMID:30768104] [10.1039/C8NR08532C]

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