Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO - ) , with an IC 50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC 50 value of 71.99 μM for ONOO - . Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor
In Vitro
Flazin significantly decreases cellular triglyceride (TG) by 12.0-22.4% compared with modeling groups and improved the TG and free fatty acid profile. Flazin efficiently reduces both cellular neutral lipid content by 17.4-53.9% and lipid droplets size by 10.0-35.3%. Flazin exhibits xanthine oxidase inhibitory with an IC 50 of 0.51 mM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.