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Fluorometholone Acetate - ≥98%, high purity , Glucocorticoid receptor agonist, CAS No.3801-06-7, Glucocorticoid receptor agonist

  • ≥98%
Item Number
F129608
Grouped product items
SKUSizeAvailabilityPrice Qty
F129608-50mg
50mg
In stock
$137.90
F129608-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$619.90

Synthetic corticosteroid

Basic Description

SynonymsFLUOROMETHOLONE ACETATE|3801-06-7|Eflone|Flarex|Oxylone acetate|Fluorometholone 17-acetate|NSC 47438|NSC-47438|9I50C3I3OK|CHEBI:78354|9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate|U-17323|U-17,323|UNII-9I50C3I3OK|AI3-528
Specifications & Purity≥98%
Biochemical and Physiological MechanismsFluorometholone Acetate is a glucocorticoid and an anti-inflammatory.Synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeAGONIST
Mechanism of actionGlucocorticoid receptor agonist
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
A glucocorticoid and anti-inflammatory.

Product Properties

ALogP2.6

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate
INCHI InChI=1S/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1
InChi Key YRFXGQHBPBMFHW-SBTZIJSASA-N
Canonical SMILES CC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)OC(=O)C
Isomeric SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)OC(=O)C
PubChem CID 240767
Molecular Weight 418.5

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
J2112556Certificate of AnalysisJul 07, 2023 F129608
J2112557Certificate of AnalysisJul 07, 2023 F129608

Chemical and Physical Properties

SolubilityDMSO 84 mg/mL Water Ethanol

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H373:Causes damage to organs through prolonged or repeated exposure

H318:Causes serious eye damage

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Solution Calculators