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Flurbiprofen - ≥98.0%(HPLC), high purity , CAS No.5104-49-4, Channel blocker of ASIC1;Inhibitor of COX-1;Inhibitor of COX-2

  • Moligand™
  • ≥98%(HPLC)
Item Number
F134483
Grouped product items
SKUSizeAvailabilityPrice Qty
F134483-1g
1g
In stock
$15.90
F134483-5g
5g
In stock
$58.90
F134483-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$106.90
F134483-25g
25g
In stock
$171.90
F134483-100g
100g
In stock
$619.90
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Potent COX inhibitor. NSAID.

View related series
ASIC1 Channel blocker COX-1 Inhibitor COX-2 Inhibitor

Basic Description

Synonymsflurbiprofen|5104-49-4|Ansaid|Froben|Antadys|2-(2-fluorobiphenyl-4-yl)propanoic acid|Flubiprofen|3-Fluoro-4-phenylhydratropic acid|Cebutid|Flurofen|2-(3-fluoro-4-phenylphenyl)propanoic acid|Flurbiprofene|Flurbiprofeno|Flurbiprofenum|Ocufen|Flurbiprofene [
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsFlurbiprofen is a mixture of S(+) and R(-) enantiomers. Flurbiprofen acts as a potent inhibitor of Cox-1 (cyclooxygenase-1) and Cox-2 (cyclooxygenase-2) (IC50 = 5 nM for LPS-induced Cox in human peripheral blood cells). The S(+) enantiomer is reported to
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeCHANNEL BLOCKER, INHIBITOR
Mechanism of actionChannel blocker of ASIC1;Inhibitor of COX-1;Inhibitor of COX-2
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

A potent inhibitor of Cox-1 and Cox-2

Product Properties

ALogP4.2

Names and Identifiers

IUPAC Name 2-(3-fluoro-4-phenylphenyl)propanoic acid
INCHI InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
InChi Key SYTBZMRGLBWNTM-UHFFFAOYSA-N
Canonical SMILES CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
Isomeric SMILES CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
RTECS DU8341000
PubChem CID 3394
Molecular Weight 244.27
Reaxy-Rn 2054451

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

9 results found

Lot NumberCertificate TypeDateItem
G2429209Certificate of AnalysisJun 26, 2024 F134483
G2429213Certificate of AnalysisJun 26, 2024 F134483
G2429214Certificate of AnalysisJun 26, 2024 F134483
C2219151Certificate of AnalysisJan 04, 2024 F134483
C2219234Certificate of AnalysisJan 04, 2024 F134483
C2219239Certificate of AnalysisJan 04, 2024 F134483
C2219241Certificate of AnalysisJan 04, 2024 F134483
C2130155Certificate of AnalysisJan 13, 2023 F134483
H2330031Certificate of AnalysisFeb 12, 2022 F134483

Chemical and Physical Properties

Solubility Soluble in DMSO (50 mg/ml), methanol (50 mg/ml), ethanol (~100 mg/ml), DMF (~100 mg/ml), and buffers of ionic strength ≥0.1 M and pH ≥7.4 (~5 mg/ml). Insoluble in water, Soluble in DMSO (50 mg/ml), methanol (50 mg/ml), ethanol (~100 mg/ml), DMF (~1
Melt Point(°C)113 °C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RTECS DU8341000
Reaxy-Rn 2054451
Merck Index 4199

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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