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F113134-5g

In stock

$15.90

F113134-10g

10g

Available within 4-8 weeks(?)

$27.90

F113134-25g

25g

In stock

$39.90

F113134-100g

100g

In stock

$143.90

F113134-500g

500g

Available within 4-8 weeks(?)

$646.90

Basic Description

Synonyms	Fmoc-Pro-OH\|Fmoc-L-proline\|71989-31-6\|N-FMOC-L-PROLINE\|(S)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID\|Fmoc-L-Pro-OH\|(2S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-2-carboxylic acid\|N-(9-Fluorenylmethoxycarbonyl)-L-proline\|
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice

Associated Targets

SLC17A5 Tbio Sialin 0 Activities

Discover Target: SLC17A5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
INCHI	InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m0/s1
InChi Key	ZPGDWQNBZYOZTI-SFHVURJKSA-N
Canonical SMILES	C1CC(N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
Isomeric SMILES	C1C[C@H](N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
WGK Germany	3
PubChem CID	688135
Molecular Weight	337.37
Beilstein	3596735

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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13 results found

Lot Number	Certificate Type	Date	Item
F2425214	Certificate of Analysis	Apr 02, 2024	F113134
F2425215	Certificate of Analysis	Apr 02, 2024	F113134
B2303403	Certificate of Analysis	Sep 30, 2022	F113134
B2303404	Certificate of Analysis	Sep 30, 2022	F113134
B2303406	Certificate of Analysis	Sep 30, 2022	F113134
B2303407	Certificate of Analysis	Sep 30, 2022	F113134
B2303408	Certificate of Analysis	Sep 30, 2022	F113134
B2303455	Certificate of Analysis	Sep 30, 2022	F113134
D2419059	Certificate of Analysis	Sep 30, 2022	F113134
D2423065	Certificate of Analysis	Sep 30, 2022	F113134
C1815051	Certificate of Analysis	Jan 27, 2022	F113134
H2208050	Certificate of Analysis	Mar 05, 2021	F113134
J2325068	Certificate of Analysis	Mar 05, 2021	F113134

Chemical and Physical Properties

Solubility	Soluble in methanol.
Specific Rotation[α]	-32.5 ° (C=1, DMF)
Melt Point(°C)	115°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

References

1. Jarvis A, Allerston CK, Jia H, Herzog B, Garza-Garcia A, Winfield N, Ellard K, Aqil R, Lynch R, Chapman C et al.. (2010) Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.. J Med Chem, 53 (5): (2215-26). [PMID:20151671]
2. Rosanna Capparelli,Alessandra Romanelli,Marco Iannaccone,Nunzia Nocerino,Raffaella Ripa,Soccorsa Pensato,Carlo Pedone,Domenico Iannelli. (2009-09-29) Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.. PloS one, 4 ((9)): (e7191-e7191). [PMID:19784377]
3. Magdalena Rudowska,Robert Wieczorek,Alicja Kluczyk,Piotr Stefanowicz,Zbigniew Szewczuk. (2013-04-24) Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons.. Journal of the American Society for Mass Spectrometry, 24 ((6)): (846-856). [PMID:23609183]
4. K R Sunil Kumar,Takashi Kamei,Tuyoshi Fukaminato,Nobuyuki Tamaoki. (2014-04-01) Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.. ACS nano, 8 ((5)): (4157-4165). [PMID:24680285]
5. Huiyuan Wang,Huixin Wang,Jianming Liang,Yifan Jiang,Qianqian Guo,Huige Peng,Qin Xu,Yongzhuo Huang. (2014-08-01) Cell-penetrating apoptotic peptide/p53 DNA nanocomplex as adjuvant therapy for drug-resistant breast cancer.. Molecular pharmaceutics, 11 ((10)): (3352-3360). [PMID:25080334]
6. Yang Li,Boi Hoa San,Julian L Kessler,Jin Hwan Kim,Qingguo Xu,Justin Hanes,Seungju Michael Yu. (2014-12-06) Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.. Macromolecular bioscience, 15 ((1)): (52-62). [PMID:25476588]
7. Christina M Jones,María Eugenia Monge,Jaeyeon Kim,Martin M Matzuk,Facundo M Fernández. (2015-01-09) Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model.. Journal of proteome research, 14 ((2)): (917-927). [PMID:25567202]
8. Gizella Csire,Lajos Nagy,Katalin Várnagy,Csilla Kállay. (2017-03-07) Copper(II) interaction with the Human Prion 103-112 fragment - Coordination and oxidation.. Journal of inorganic biochemistry, 170 (195-201). [PMID:28260678]
9. Stefan Eissler,Markus Kley,Dirk Bächle,Günther Loidl,Thomas Meier,Daniel Samson. (2017-06-22) Substitution determination of Fmoc-substituted resins at different wavelengths.. Journal of peptide science : an official publication of the European Peptide Society, 23 ((10)): (757-762). [PMID:28635051]
10. Zdenek Kukacka,Marius Iurascu,Loredana Lupu,Hendrik Rusche,Mary Murphy,Lorenzo Altamore,Fabio Borri,Stefan Maeser,Anna Maria Papini,Julia Hennermann,Michael Przybylski. (2018-02-24) Antibody Epitope of Human α-Galactosidase\u2005A Revealed by Affinity Mass Spectrometry: A Basis for Reversing Immunoreactivity in Enzyme Replacement Therapy of Fabry Disease.. ChemMedChem, 13 ((9)): (909-915). [PMID:29473701]
11. Jianhao Wang,Zhilan Zhu,Lin Qiu,Jianpeng Wang,Xiang Wang,Qicai Xiao,Jiang Xia,Li Liu,Xiaoqian Liu,Wei Feng,Jinmei Wang,Peng Miao,Liqian Gao. (2018-04-17) A CE-FL based method for real-time detection of in-capillary self-assembly of the nanoconjugates of polycysteine ligand and quantum dots.. Nanotechnology, 29 ((27)): (274001-274001). [PMID:29658885]
12. Fan Gao,Chi Zhang,Wen-Xiu Qiu,Xue Dong,Di-Wei Zheng,Wei Wu,Xian-Zheng Zhang. (2018-08-22) PD-1 Blockade for Improving the Antitumor Efficiency of Polymer-Doxorubicin Nanoprodrug.. Small (Weinheim an der Bergstrasse, Germany), 14 ((37)): (e1802403-e1802403). [PMID:30129176]
13. Lucas L Bennink,Yang Li,Bumjin Kim,Ik Jae Shin,Boi Hoa San,Maurizio Zangari,Donghoon Yoon,S Michael Yu. (2018-08-28) Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging.. Biomaterials, 183 (67-76). [PMID:30149231]
14. Hong Cheng,Gui-Ling Fan,Jing-Hao Fan,Rong-Rong Zheng,Lin-Ping Zhao,Ping Yuan,Xiao-Ya Zhao,Xi-Yong Yu,Shi-Ying Li. (2018-12-24) A Self-Delivery Chimeric Peptide for Photodynamic Therapy Amplified Immunotherapy.. Macromolecular bioscience, 19 ((4)): (e1800410-e1800410). [PMID:30576082]
15. Karthik Nadendla,Bhagyesh R Sarode,Simon H Friedman. (2019-05-24) Hydrophobic Tags for Highly Efficient Light-Activated Protein Release.. Molecular pharmaceutics, 16 ((7)): (2922-2928). [PMID:31117739]
16. Gizella Csire,Ildikó Turi,Imre Sóvágó,Eszter Kárpáti,Csilla Kállay. (2019-12-07) Complex formation processes and metal ion catalyzed oxidation of model peptides related to the metal binding site of the human prion protein.. Journal of inorganic biochemistry, 203 (110927-110927). [PMID:31810042]
17. Michał Padjasek,Maciej Maciejczyk,Michał Nowakowski,Olga Kerber,Maciej Pyrka,Wiktor Koźmiński,Artur Krężel. (2019-12-18) Metal Exchange in the Interprotein ZnII -Binding Site of the Rad50 Hook Domain: Structural Insights into CdII -Induced DNA-Repair Inhibition.. Chemistry (Weinheim an der Bergstrasse, Germany), 26 ((15)): (3297-3313). [PMID:31846102]
18. Jingwen Song,Chengqian Yuan,Tifeng Jiao,Ruirui Xing,Mengyao Yang,Dave J Adams,Xuehai Yan. (2020-01-30) Multifunctional Antimicrobial Biometallohydrogels Based on Amino Acid Coordinated Self-Assembly.. Small (Weinheim an der Bergstrasse, Germany), 16 ((8)): (e1907309-e1907309). [PMID:31994844]
19. Yun Song,Lisbeth Dagil,Louise Fairall,Naomi Robertson,Mingxuan Wu,T J Ragan,Christos G Savva,Almutasem Saleh,Nobuhiro Morone,Micha B A Kunze,Andrew G Jamieson,Philip A Cole,D Flemming Hansen,John W R Schwabe. (2020-02-27) Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.. Cell reports, 30 ((8)): (2699-2711). [PMID:32101746]
20. Barbara Prandi,Tullia Tedeschi,Silvia Folloni,Gianni Galaverna,Stefano Sforza. (2017-03-16) Peptides from gluten digestion: A comparison between old and modern wheat varieties.. Food research international (Ottawa, Ont.), 91 (92-102). [PMID:28290332]

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Fmoc-Pro-OH - 98%, high purity , CAS No.71989-31-6

Basic Description

Associated Targets

SLC17A5 Tbio Sialin 0 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

more

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator