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Foliglurax monohydrochloride - 10mM in DMSO, high purity , CAS No.2133294-96-7(DMSO)

  • 10mM in DMSO
Item Number
F655779
Grouped product items
SKUSizeAvailabilityPrice Qty
F655779-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$495.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsFoliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator ( mGluR4 PAM) , with an EC 50 of 79 nM. Antiparkinsonian effect.
Storage TempDesiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator ( mGluR4 PAM) , with an EC 50 of 79 nM Antiparkinsonian effect

In Vitro

Foliglurax, a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:mGlu 4 79 nM (EC 50 )

Names and Identifiers

Canonical SMILES O/N=C1C=C(C2=CC3=C(C=CS3)C=N2)OC4=CC=C(CCCN5CCOCC5)C=C\\14.Cl
Molecular Weight 457.97

Certificates

C of A & Other Certificates

Related Documents

Solution Calculators