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Fondaparinux sodium - 98%, high purity , Antithrombin-III activator, CAS No.114870-03-0, Antithrombin-III activator

Moligand™
≥98%

CAS#: 114870-03-0
Formula: C₃₁H₄₃N₃Na₁₀O₄₉S₈
Molecular Weight: 1728.08
PubChem CID: 636380

Item Number

F302246

Grouped product items
SKU	Size	Availability	Price
F302246-5mg	5mg	In stock	$90.90
F302246-10mg	10mg	In stock	$155.90
F302246-25mg	25mg	In stock	$338.90
F302246-50mg	50mg	In stock	$599.90
F302246-100mg	100mg	In stock	$1,080.90

View related series

serpin family C member 1 Activator

Basic Description

Synonyms	Fondaparinux sodium\|114870-03-0\|Fondaparin sodium\|Arixtra\|Quixidar\|SR-90107A\|Xantidar\|Fondaparinux sodium for assay\|SR 90107A\|Org 31540\|Fondaparinux sodium identification\|Org-31540\|X0Q6N9USOZ\|IC-851589\|Fondaparinux (sodium)\|FONDAPARINUX SODIUM (MART.)\|FON
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. F
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Antithrombin-III activator
Product Description	Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.

Associated Targets

F10 Tclin Coagulation factor X 0 Activities

Discover Target: F10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SERPINC1 Tclin Antithrombin-III 1 Activities

Discover Target: SERPINC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	decasodium;(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-2-carboxylato-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-5-sulfonatooxyoxan-3-yl]oxy-5-(sulfonatoamino)-4-sulfonatooxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4,5-dihydroxyoxane-2-carboxylate
INCHI	InChI=1S/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56;;;;;;;;;;/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68);;;;;;;;;;/q;10*+1/p-10/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-;;;;;;;;;;/m1........../s1
InChi Key	XEKSTYNIJLDDAZ-JASSWCPGSA-D
Canonical SMILES	COC1C(C(C(C(O1)COS(=O)(=O)[O-])OC2C(C(C(C(O2)C(=O)[O-])OC3C(C(C(C(O3)COS(=O)(=O)[O-])OC4C(C(C(C(O4)C(=O)[O-])OC5C(C(C(C(O5)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O)NS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Isomeric SMILES	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)[O-])O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)[O-])O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)[O-])O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O)NS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
PubChem CID	636380
Molecular Weight	1728.08

DrugBank Ligand

PubChem CID

CAS Registry No.

ChEMBL Ligand

Wikipedia

RCSB PDB Ligand

PEP

Reactome Reaction

R-HSA-140791, R-HSA-140806, R-HSA-140870, R-HSA-140872

Reactome Drug

R-ALL-9693054

DrugCentral Ligand

1236

Certificates

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5 results found

Lot Number	Certificate Type	Date	Item
K2202679	Certificate of Analysis	Sep 06, 2022	F302246
K2202680	Certificate of Analysis	Sep 06, 2022	F302246
K2202681	Certificate of Analysis	Sep 06, 2022	F302246
K2202682	Certificate of Analysis	Sep 06, 2022	F302246
K2202732	Certificate of Analysis	Sep 06, 2022	F302246

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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