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Home Oncology Tumor Biomarkers Enzymes Fosamprenavir Calcium Salt - ≥95%, high purity , Human immunodeficiency virus type 1 protease inhibitor, CAS No.226700-81-8, Human immunodeficiency virus type 1 protease inhibitor
Fosamprenavir Calcium Salt - ≥95%, high purity , Human immunodeficiency virus type 1 protease inhibitor, CAS No.226700-81-8, Human immunodeficiency virus type 1 protease inhibitor
a water soluble protease inhibitor
Basic Description Synonyms DTXCID8026777 | (3S)-TETRAHYDRO-3-FURYL ((alphaS)-alpha-((1R)-1-HYDROXY-2-(N1-ISOBUTYLSULFANILAMIDO)ETHYL)PHENETHYL)CARBAMATE, CALCIUM PHOSPHATE (ESTER) (1:1) | CAS-226700-81-8 | Fosamprenavir (Calcium Salt) | Lexiva | (3S)-Tetrahydro-3-furyl ((alphaS)-al Specifications & Purity ≥95% Biochemical and Physiological Mechanisms Fosamprenavir calcium is an HIV protease inhibitor anti-retroviral. It is a water soluble phosphate ester prodrug of amprenavir, the active agent. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action Human immunodeficiency virus type 1 protease inhibitor Product Description
Fosamprenavir Calcium Salt is a HIV protease inhibitor that is water soluble prodrug of amprenavir.
Names and Identifiers Pubchem Sid 504757007 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504757007 IUPAC Name calcium;[(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate INCHI InChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/q;+2/p-2/t21-,23-,24+;/m0./s1 InChi Key PMDQGYMGQKTCSX-HQROKSDRSA-L Canonical SMILES CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] Isomeric SMILES CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] RTECS EY8573300 PubChem CID 131535 Molecular Weight 623.67
Chemical and Physical Properties Solubility Soluble in aqueous HCl, and DMF. Sensitivity Moisture sensitive. Refractive Index n20D1.61 (Predicted) Melt Point(°C) >257° C (dec.)
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H351: Suspected of causing cancer
H373: Causes damage to organs through prolonged or repeated exposure
H361: Suspected of damaging fertility or the unborn child
H362: May cause harm to breast-fed children
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P362+P364: Take off contaminated clothing and wash it before reuse.
P263: Avoid contact during pregnancy/while nursing.
P203: Obtain, read and follow all safety instructions before use.
P318: if exposed or concerned, get medical advice.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
RTECS EY8573300 RIDADR NONHforallmodesoftransport
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