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Fosfomycin Disodium Salt - >98.0%(HPLC), high purity , CAS No.26016-99-9

≥98%(HPLC)

CAS#: 26016-99-9
Formula: C₃H₅Na₂O₄P
Molecular Weight: 182.02
Beilstein Registry Number: 4604425
EC Number: 247-409-2
MDL number: MFCD22741288
PubChem CID: 73491

Item Number

F133769

Grouped product items
SKU	Size	Availability	Price
F133769-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$77.90
F133769-25g	25g	In stock	$261.90
F133769-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$940.90

Broad spectrum antimicrobial agent

View related series

Element classified compounds Phosphonic acids

Basic Description

Synonyms	Fosfomycin disodium\|Fosfomycin sodium\|26016-99-9\|Phosphonemycin\|Fosfomycin disodium salt\|Phosphomycin disodium salt\|Veramina\|Disodium phosphonomycin\|Fosfomycin sodium [JAN]\|Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate\|Disodium fosfomycin\|Priomicina\|Fosfo
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine

Associated Targets

KPNB1 Tbio Importin subunit beta-1 0 Activities

Discover Target: KPNB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A 0 Activities

Discover Target: KDM4A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	disodium;[(2R,3S)-3-methyloxiran-2-yl]-dioxido-oxo-λ5-phosphane
INCHI	InChI=1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
InChi Key	QZIQJIKUVJMTDG-JSTPYPERSA-L
Canonical SMILES	CC1C(O1)P(=O)([O-])[O-].[Na+].[Na+]
Isomeric SMILES	C[C@H]1[C@H](O1)P(=O)([O-])[O-].[Na+].[Na+]
Alternate CAS	23155-02-4
PubChem CID	73491
Molecular Weight	182.02
Beilstein	4604425

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
D2407258	Certificate of Analysis	Mar 09, 2024	F133769
B2423220	Certificate of Analysis	Feb 04, 2024	F133769
B2423221	Certificate of Analysis	Feb 04, 2024	F133769
B2423222	Certificate of Analysis	Feb 04, 2024	F133769
B2423223	Certificate of Analysis	Feb 04, 2024	F133769
B2423224	Certificate of Analysis	Feb 04, 2024	F133769
F2102330	Certificate of Analysis	Mar 13, 2023	F133769
F2102331	Certificate of Analysis	Mar 13, 2023	F133769
J2228520	Certificate of Analysis	Aug 26, 2022	F133769
J2228527	Certificate of Analysis	Aug 26, 2022	F133769
J2228528	Certificate of Analysis	Aug 26, 2022	F133769
C2202199	Certificate of Analysis	Apr 23, 2021	F133769

Solubility

Freely soluble in water or aqueous solution；Slightly soluble in methanol

Sensitivity

Heat sensitive；Light sensitive

Specific Rotation[α]

-5° (C=5,H2O)

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H302:Harmful if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H362:May cause harm to breast-fed children
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

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