FTIDC - ≥98%(HPLC), high purity , CAS No.873551-53-2, Allosteric modulator of mGlu 1 receptor

Item Number

F288677

• Synonyms: 4-[1-(2-Fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydro-N-methyl-N-(1-methylethyl)-1(2H)-pyridinecarboxamide
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Potent and selective mGlu1receptor negative allosteric modulator (IC50values are 5.8 and 6200 nM for mGlu1and mGlu5respectively). Also acts as an mGlu1receptor inverse agonist (IC50= 7 nM) in the absence of ligand. Exhibits no effect at group II/III mGlu
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ALLOSTERIC MODULATOR
• Mechanism of action: Allosteric modulator of mGlu 1 receptor

Product Description

Product description

FTIDC is an orally active, noncompetitive, selective allosteric metabotropic glutamate receptor (mGluR) 1 antagonist with an IC50 of 5.8 nM for human mGluR1a. FTIDC has no species differences in its antagonistic activity on recombinant human, mouse, and rat mGluR1.