Furamidine dihydrochloride - 98%, high purity , CAS No.55368-40-6

Item Number

F286803

Grouped product items
SKU	Size	Availability	Price	Qty
F286803-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$61.90
F286803-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$256.90

Selective PRMT1 inhibitor

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Basic Description

Synonyms	DB 75 \| DB75 \| NSC 305831 \| WR199385 \| 4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride \| DTXSID90970703 \| 4,4'-(Furan-2,5-diyl)dibenzimidamidedihydrochloride \| 4,4'-(2,5-Furandiyl)dibenzenecarboximidamide dihydrochloride \| 4,
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50= 9.4μM). Exhibits selectivity over PRMT5, PRMT6 and CARM1 (IC50values are 166, 283 and >400μM respectively). Inhibits cell proliferation in leukemia cell lines. Cell-permeable.
Storage Temp	Protected from light,Store at -20°C,Argon charged,Desiccated
Shipped In	Ice chest + Ice pads

Names and Identifiers

IUPAC Name	4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride
INCHI	InChI=1S/C18H16N4O.2ClH/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22;;/h1-10H,(H3,19,20)(H3,21,22);2*1H
InChi Key	VXNYQUQHOUERTR-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
Isomeric SMILES	C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
PubChem CID	9799856
Molecular Weight	377.27

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
D2301301	Certificate of Analysis	Feb 03, 2023	F286803
D2301332	Certificate of Analysis	Feb 03, 2023	F286803
D2301303	Certificate of Analysis	Feb 03, 2023	F286803

Solubility

Solvent:water, Max Conc. mg/mL: 18.86, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 18.86, Max Conc. mM: 50

Sensitivity

light sensitive；Moisture sensitive

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Basic Description