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Furosemide sodium - 10mM in DMSO, high purity , CAS No.41733-55-5
GABAA receptor Selective Activators | Agonists | Antagonists
Basic Description Synonyms Sodium furosemide | Furosemide sodium | 41733-55-5 | Furosemide (sodium) | 101EM454S7 | sodium;4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate | Frosemide sodium | UNII-101EM454S7 | EINECS 255-526-5 | SCHEMBL6751173 | HY-B0135A | DTXSID90194528 | FUROSEMIDE SODIUM [WHO-DD Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description Information
Furosemide (Frusemide) sodium is a potent and orally active inhibitor ofNa-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist ofgamma-aminobutyric acid type A (GABAA) receptor.
Targets
NKCC ; GABAA receptor
Product Properties ALogP -0.071 HBD Count 2 Rotatable Bond 5
Names and Identifiers IUPAC Name sodium;4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate INCHI InChI=1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);/q;+1/p-1 InChi Key DLFCAVBMDSKMEY-UHFFFAOYSA-M Canonical SMILES C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)[O-])S(=O)(=O)N)Cl.[Na+] Isomeric SMILES C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)[O-])S(=O)(=O)N)Cl.[Na+] PubChem CID 23673593 Molecular Weight 352.73
Chemical and Physical Properties DMSO(mg / mL) Max Solubility 71 DMSO(mM) Max Solubility 201.287103450231 Water(mg / mL) Max Solubility 71 Water(mM) Max Solubility 201.287103450231
Safety and Hazards(GHS) Pictogram(s) GHS08 Signal Warning Hazard Statements H341: Suspected of causing genetic defects
H412: Harmful to aquatic life with long lasting effects
H361: Suspected of damaging fertility or the unborn child
H362: May cause harm to breast-fed children
Precautionary Statements P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P281: Use personal protective equipment as required.
P270: Do not eat, drink or smoke when using this product.
P263: Avoid contact during pregnancy/while nursing.
P203: Obtain, read and follow all safety instructions before use.
P318: if exposed or concerned, get medical advice.
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