Skip to the beginning of the images gallery

G418 Solution - 25mg/ml, Sterilized, high purity , CAS No.108321-42-2

4 Citations

25mg/ml, Sterilized

CAS#: 108321-42-2
Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄
Molecular Weight: 692.71
PubChem CID: 16218858

Item Number

G301863

Grouped product items
SKU	Size	Availability	Price	Qty
G301863-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$69.90

Discover G418 Solution by Aladdin Scientific in 25mg/ml, Sterilized for only $69.90. Available - in Ligands at Aladdin Scientific. Tags: .

Basic Description

Synonyms	AC-32603 \| G 418 disulfate salt \| (2S,3S,4S,5S)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid \| C20H40N4O10.2H2SO4 \| G
Specifications & Purity	25mg/ml, Sterilized
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Names and Identifiers

IUPAC Name	(2S,3S,4S,5S)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
INCHI	InChI=1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;21-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
InChi Key	UHEPSJJJMTWUCP-NKCAIAFTSA-N
Canonical SMILES	CC(C1C(C(C(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
Isomeric SMILES	CC([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@H]3[C@H]([C@@H]([C@](CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
WGK Germany	3
PubChem CID	16218858
Molecular Weight	692.71

Lot Number

Certificate Type

Date

Item

L2106991

Certificate of Analysis

Jan 10, 2022

G301863

Specific Rotation[α]

111 ° (C=0.3, H2O)

Melt Point(°C)

138-144°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H335:May cause respiratory irritation H373:Causes damage to organs through prolonged or repeated exposure H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H360:May damage fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.
WGK Germany	3

Citations of This Product

1. Han Sijia, Jin Xueying, Hu Tianyu, Chi Feng. (2023) ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop. CARCINOGENESIS, [PMID:37326327]
2. Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi. (2023) LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway. ONCOLOGY REPORTS, 49 (3): (1-14). [PMID:36799186]
3. Jing Zhou, Tongyu Wu, Chun Li, Zhuozhou Hu, Liang Han, Xiangxiang Li, Jingjing Liu, Wenyang Zhao, Jia Kang, Xinping Chen. (2023) Alfuzosin ameliorates diabetes by boosting PGK1 activity in diabetic mice. LIFE SCIENCES, 317 (121491). [PMID:36758669]
4. Zhuozhou Hu, Jing Zhou, Liang Han, Xiangxiang Li, Chun Li, Tongyu Wu, Jingjing Liu, Wenyang Zhao, Jia Kang, Xinping Chen. (2022) Acyclovir alleviates insulin resistance via activating PKM1 in diabetic mice. LIFE SCIENCES, 304 (120725). [PMID:35751919]

References

1. Han Sijia, Jin Xueying, Hu Tianyu, Chi Feng. (2023) ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop. CARCINOGENESIS, [PMID:37326327]
2. Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi. (2023) LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway. ONCOLOGY REPORTS, 49 (3): (1-14). [PMID:36799186]
3. Jing Zhou, Tongyu Wu, Chun Li, Zhuozhou Hu, Liang Han, Xiangxiang Li, Jingjing Liu, Wenyang Zhao, Jia Kang, Xinping Chen. (2023) Alfuzosin ameliorates diabetes by boosting PGK1 activity in diabetic mice. LIFE SCIENCES, 317 (121491). [PMID:36758669]
4. Zhuozhou Hu, Jing Zhou, Liang Han, Xiangxiang Li, Chun Li, Tongyu Wu, Jingjing Liu, Wenyang Zhao, Jia Kang, Xinping Chen. (2022) Acyclovir alleviates insulin resistance via activating PKM1 in diabetic mice. LIFE SCIENCES, 304 (120725). [PMID:35751919]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

G418 Solution - 25mg/ml, Sterilized, high purity , CAS No.108321-42-2

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties