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Gabexate Mesylate - ≥99%, high purity , CAS No.56974-61-9

  • ≥99%
Item Number
G129271
Grouped product items
SKUSizeAvailabilityPrice Qty
G129271-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$28.90
G129271-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$117.90
G129271-100mg
100mg
In stock
$391.90
G129271-250mg
250mg
In stock
$882.90
G129271-1g
1g
In stock
$3,175.90
G129271-5g
5g
In stock
$14,288.90

General serine protease inhibitor

Basic Description

SynonymsGabexate mesylate|56974-61-9|Gabexate mesilate|Gabexate (mesylate)|Gabexate Methanesulfonate|FOY|56974-61-9 (mesylate)|Gabexate mesilate [JAN]|CHEMBL1398351|DTXSID0045591|NCGC00017121-01|ethyl 4-((6-guanidinohexanoyl)oxy)benzoate methanesulfonate|CAS-5697
Specifications & Purity≥99%
Biochemical and Physiological MechanismsGeneral serine protease inhibitor (K i values are 3.4 nM, 5, 1.8 µM and 2.6 mM at tryptase, thrombin, tyrpsin and kallikrein serine proteases respectively). Additionally inhibits nitric oxide synthase. Displays antithrombotic activity and antitumor effect
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Note5mg卖完停产,不再备货。Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Gabexate mesylate
Serine protease inhibitor.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KLK7 Tchem Kallikrein-7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid
INCHI InChI=1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
InChi Key DNTNDFLIKUKKOC-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
Isomeric SMILES CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
PubChem CID 6604561
Molecular Weight 417.48

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
I2227298Certificate of AnalysisJul 15, 2024 G129271
I2227299Certificate of AnalysisJul 15, 2024 G129271
I2227300Certificate of AnalysisJul 15, 2024 G129271
I2227303Certificate of AnalysisJul 15, 2024 G129271
H1520105Certificate of AnalysisMar 09, 2023 G129271
D2222114Certificate of AnalysisMay 02, 2022 G129271
D2222123Certificate of AnalysisMay 02, 2022 G129271
D2222125Certificate of AnalysisMay 02, 2022 G129271

Chemical and Physical Properties

SolubilityDMSO 83 mg/mL Water 12 mg/mL Ethanol 83 mg/mL
Melt Point(°C)91 °C

Safety and Hazards(GHS)

Merck Index 4320

Related Documents

Solution Calculators