GAK inhibitor 49 hydrochloride - 98%, high purity , CAS No.G659460

Item Number

G659460

Grouped product items
SKU	Size	Availability	Price
G659460-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$200.90
G659460-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
G659460-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$650.90
G659460-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$950.90
G659460-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,350.90

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Basic Description

Specifications & Purity	98%
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Product Description	GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a K i of 0.54 nM and a cell IC 50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2. Appearance:Solid In Vitro:GAK inhibitor 49 (compound 49) hydrochloride shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC 50 s of 28, 63 and >100μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a K i of 0.54 nM and a cell IC 50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2.

Canonical SMILES

COC1=C(OC)C(OC)=CC(NC2=CC=NC3=CC(OC)=C(OC)C=C23)=C1.[H]Cl

Molecular Weight

406.86

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Basic Description