Click Here for 5% Off Your First Aladdin Purchase!

Gallic acid - 99%, high purity , CAS No.149-91-7, Inhibitor of carbonic anhydrase 1

  • Moligand™
  • ≥99%
Item Number
G131992
Grouped product items
SKUSizeAvailabilityPrice Qty
G131992-5g
5g
In stock
$9.90
G131992-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$29.90
G131992-100g
100g
In stock
$57.90
G131992-500g
500g
In stock
$112.90

Phase II enzyme inducer. COX inhibitor.

Basic Description

SynonymsGallic acid|3,4,5-Trihydroxybenzoic acid|149-91-7|gallate|Benzoic acid, 3,4,5-trihydroxy-|Gallic acid, tech.|Kyselina gallova|Pyrogallol-5-carboxylic acid|GALOP|HSDB 2117|CCRIS 5523|3,4,5-Trihydroxybenzoate|MFCD00002510|NSC 674319|CHEBI:30778|Kyselina 3,4
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsPhase II enzyme inducer. COX inhibitor. Carbonic anhydrase inhibitor (IC 50 = 4 μM). Shows antioxidant activity. Orally active.
Storage TempProtected from light,Argon charged
Shipped InNormal
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of carbonic anhydrase 1
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Gallic acid is an antiinflammatory and Cox (cyclooxygease inhibitory substance found in plants and has been shown to Induce apoptosis in human lung cancer cells. It is cytotoxic to PC14 AND MKN45 human cancer cell lines.
A cyclooxygease inhibitor substance found in plants.

Associated Targets

DPP4 Tclin Dipeptidyl peptidase 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SQLE Tchem Squalene monooxygenase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ESR1 Tclin Estrogen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA5A Tclin Carbonic anhydrase 5A, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PSMB5 Tclin Proteasome subunit beta type-5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MET Tclin Hepatocyte growth factor receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TLR2 Tchem Toll-like receptor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SNCA Tchem Alpha-synuclein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SELE Tchem E-selectin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA5B Tclin Carbonic anhydrase 5B, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA6 Tclin Carbonic anhydrase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA13 Tclin Carbonic anhydrase 13 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA1 Tclin Carbonic anhydrase 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA3 Tclin Carbonic anhydrase 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA4 Tclin Carbonic anhydrase 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA12 Tclin Carbonic anhydrase 12 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA14 Tclin Carbonic anhydrase 14 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA9 Tclin Carbonic anhydrase 9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA7 Tclin Carbonic anhydrase 7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP19A1 Tclin Aromatase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADAM17 Tchem Disintegrin and metalloproteinase domain-containing protein 17 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACE Tclin Angiotensin-converting enzyme 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AKR1B1 Tclin Aldose reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APP Tclin Amyloid-beta A4 protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

F2 Tclin Prothrombin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLS Tchem Glutaminase kidney isoform, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLA2G7 Tchem Platelet-activating factor acetylhydrolase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488179516
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179516
IUPAC Name 3,4,5-trihydroxybenzoic acid
INCHI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
InChi Key LNTHITQWFMADLM-UHFFFAOYSA-N
Canonical SMILES C1=C(C=C(C(=C1O)O)O)C(=O)O
Isomeric SMILES C1=C(C=C(C(=C1O)O)O)C(=O)O
WGK Germany 2
RTECS LW7525000
PubChem CID 370
Molecular Weight 170.12
Beilstein 2050274

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

22 results found

Lot NumberCertificate TypeDateItem
H2423012Certificate of AnalysisAug 30, 2024 G131992
K2229875Certificate of AnalysisAug 20, 2024 G131992
K2229833Certificate of AnalysisAug 20, 2024 G131992
K2229832Certificate of AnalysisAug 20, 2024 G131992
K2229780Certificate of AnalysisAug 20, 2024 G131992
I2222790Certificate of AnalysisJul 15, 2024 G131992
I2222789Certificate of AnalysisJul 15, 2024 G131992
B2303912Certificate of AnalysisFeb 07, 2023 G131992
L2031357Certificate of AnalysisOct 21, 2022 G131992
I2222788Certificate of AnalysisJul 23, 2022 G131992
I2222791Certificate of AnalysisJul 23, 2022 G131992
I2223570Certificate of AnalysisJul 23, 2022 G131992
J2327264Certificate of AnalysisJul 23, 2022 G131992
K22291017Certificate of AnalysisJul 23, 2022 G131992
G2313212Certificate of AnalysisJul 23, 2022 G131992
H2203378Certificate of AnalysisJun 16, 2022 G131992
H2203375Certificate of AnalysisJun 16, 2022 G131992
I2322005Certificate of AnalysisJun 16, 2022 G131992
H2203374Certificate of AnalysisJun 16, 2022 G131992
H2203373Certificate of AnalysisJun 16, 2022 G131992
B2218027Certificate of AnalysisApr 12, 2021 G131992
B2209116Certificate of AnalysisApr 12, 2021 G131992

more

Chemical and Physical Properties

SolubilitySoluble in water (11.5 mg/ml), ethanol, acetone, and Alcohol. Insoluble in chloroform.
SensitivityLight & Moisture Sensitive.Air sensitive
Melt Point(°C)251 °C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H318:Causes serious eye damage

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS LW7525000

Related Documents

References

1. Yan, G. L., Zhou, Y. Z., Zhao, L. Q. and Wang, W..  (2022)  Phenolic contents and antioxidant activities of solvent extracts from four edible flowers.  INTERNATIONAL FOOD RESEARCH JOURNAL,  29  (5): (1155-1167).  [PMID:]

Solution Calculators