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gamma-secretase modulator 2 - 10mM in DMSO, high purity , CAS No.1093978-89-2(DMSO)

  • 10mM in DMSO
Item Number
G655472
Grouped product items
SKUSizeAvailabilityPrice Qty
G655472-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$605.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value:Target: γ-secretase γ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease.

Associated Targets

SLC6A4 Tclin Sodium-dependent serotonin transporter 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES CC1=CN(C=N1)C2=C(C=C(C=C2)C3=CN(N=N3)C4CCC5=C(C=CC=C5F)N(C4=O)CC(F)(F)F)OC
Molecular Weight 514.47

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