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GCN2-IN-1 - ≥98.0%, high purity , CAS No.1448693-69-3

  • ≥98%
Item Number
G649297
Grouped product items
SKUSizeAvailabilityPrice Qty
G649297-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$85.90
G649297-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$180.90
G649297-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$280.90
G649297-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$580.90
G649297-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$980.90
G649297-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,780.90

Basic Description

Specifications & Purity≥98.0%
Storage TempStore at -20°C
Shipped InDry ice
Product Description

GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase ( GCN2 ) inhibitor with an IC 50 of <0.3 μM in the enzyme assay and an IC 50 of 0.3-3 μM in the cell assay

In Vitro

GCN2-IN-1 (Compound A-92) is a GCN2 inhibitor, which may be useful as a chemotherapeutic drug for the treatment of cancer. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:eIF2

Names and Identifiers

IUPAC Name 3-(1H-indazol-6-yl)-N-[1-(oxan-4-yl)pyrazol-4-yl]triazolo[4,5-d]pyrimidin-5-amine
INCHI InChI=1S/C19H18N10O/c1-2-15(7-16-12(1)8-21-25-16)29-18-17(26-27-29)10-20-19(24-18)23-13-9-22-28(11-13)14-3-5-30-6-4-14/h1-2,7-11,14H,3-6H2,(H,21,25)(H,20,23,24)
InChi Key CFNFLNGJQOHNPR-UHFFFAOYSA-N
Canonical SMILES C1COCCC1N2C=C(C=N2)NC3=NC=C4C(=N3)N(N=N4)C5=CC6=C(C=C5)C=NN6
Isomeric SMILES C1COCCC1N2C=C(C=N2)NC3=NC=C4C(=N3)N(N=N4)C5=CC6=C(C=C5)C=NN6
PubChem CID 89720372
Molecular Weight 402.41

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 60 mg/mL (149.10 mM; Need ultrasonic and warming)

Related Documents

Solution Calculators