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GITR/CD357 Rat mAb (Biotin)

  • ExactAb™
  • Validated
  • 0.5 mg/mL
Features and benefits
  • Short Overview:

    mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (Biotin); Flow

  • Species reactivity(Reacts with): Mouse
  • Isotype: Rat IgG2b
    Application:
  • Flow Cytometry
Item Number
Ab190289
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab190289-10μg (Trial Size)
Apply for free trial size(?)
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10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$36.90
Ab190289-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$174.90
Ab190289-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$72.90

mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (Biotin); Flow

Basic Description

Product NameGITR/CD357 Rat mAb (Biotin)
Specifications & PurityExactAb™, Validated, 0.5 mg/mL
Biochemical and Physiological MechanismsReceptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Host speciesRat
SpecificityGITR/CD357
ImmunogenMouse CD25+ CD4+ T cells
Positive ControlFlow: C57BL/6 mouse splenocytes.
ConjugationBiotin
GradeExactAb™, Validated
Product Description

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow

Product Properties

IsotypeRat IgG2b
Light Chain Typelambda
Purification MethodProtein G purified
Concentration0.5 mg/mL
Storage TempStore at 2-8°C,Protected from light,Freeze prohibited
Shipped InWet ice
Stability And StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Images

GITR/CD357 Rat mAb (Biotin) (Ab190289) - Flow Cytometry
Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (APC) (Ab179012) and either Rat IgG Isotype Control Antibody (Biotin) (Ab180310; Left panel) or GITR/CD357 Rat mAb (Biotin) (Ab190289; Right panel) at 1 μg/mL. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Total viable cells were used for analysis.

Associated Targets

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
Flow

≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators