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Orphan and other 7TM receptors
G protein-coupled receptors (GPCRs)
GIV3727 , CAS No.G610563, Antagonist of TAS2R31;Antagonist of TAS2R40;Antagonist of TAS2R43

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GIV3727 , CAS No.G610563, Antagonist of TAS2R31;Antagonist of TAS2R40;Antagonist of TAS2R43

Moligand™

PubChem CID: 25099817

Item Number

G610563

Grouped product items
SKU	Size	Availability	Price	Qty
G610563-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
G610563-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

TAS2R31 Antagonist TAS2R40 Antagonist TAS2R43 Antagonist

Basic Description

Synonyms	4-(2,2,3-trimethylcyclopentyl)butanoic acid\|957136-80-0\|GIV3727\|GTPL9112\|SCHEMBL1427280\|DTXSID10893723\|LYFXCRCUENNESS-UHFFFAOYSA-N\|AKOS026207949\|4-(2,2,3-trimethylcyclopentyl)butanoicacid\|HY-124956\|4-(2,2,3-Trimethylcyclopentyl)-Buttersaure\|CS-0089731\|EN3
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of TAS2R31;Antagonist of TAS2R40;Antagonist of TAS2R43

Associated Targets

TAS2R40 Tchem Taste receptor type 2 member 40 0 Activities

Discover Target: TAS2R40

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R43 Tchem Taste receptor type 2 member 43 0 Activities

Discover Target: TAS2R43

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 0 Activities

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4-(2,2,3-trimethylcyclopentyl)butanoic acid
INCHI	InChI=1S/C12H22O2/c1-9-7-8-10(12(9,2)3)5-4-6-11(13)14/h9-10H,4-8H2,1-3H3,(H,13,14)
InChi Key	LYFXCRCUENNESS-UHFFFAOYSA-N
Canonical SMILES	CC1CCC(C1(C)C)CCCC(=O)O
Isomeric SMILES	CC1CCC(C1(C)C)CCCC(=O)O
PubChem CID	25099817

Database links

PubChem CID	25099817
GPCRdb Ligand	GIV3727

Certificates

Certificate of Analysis(COA)

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References

1. Slack JP, Brockhoff A, Batram C, Menzel S, Sonnabend C, Born S, Galindo MM, Kohl S, Thalmann S, Ostopovici-Halip L et al.. (2010) Modulation of bitter taste perception by a small molecule hTAS2R antagonist.. Curr Biol, 20 (12): (1104-9). [PMID:20537538]

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