| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| G650882-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $780.90 |
| Specifications & Purity | 97% |
|---|---|
| Storage Temp | Protected from light,Store at -20°C |
| Shipped In | Dry ice |
| Product Description | Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria. In Vitro Givosiran is conjugated to a trivalent N-acetylgalactosamine ligand, which binds specifically to the asialoglycoprotein receptor, enabling targeted delivery to hepatocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
| Canonical SMILES | [Givosiran] |
|---|---|
| Molecular Weight | 16300.6 (AS: 7563.9 + SS: 8736.7) |
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