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GLPG2534 - 98%, high purity , CAS No.2095615-97-5, Inhibitor of interleukin 1 receptor associated kinase 4

  • Moligand™
  • ≥98%
Item Number
G610581
Grouped product items
SKUSizeAvailabilityPrice Qty
G610581-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
G610581-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
G610581-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
G610581-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
G610581-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,369.90

Basic Description

SynonymsGLPG-2534
Specifications & Purity≥98%
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of interleukin 1 receptor associated kinase 4
Product Description

GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4. GLPG2534 can be used for the research of inflammatory skin diseases

Associated Targets

IRAK4 Tchem Interleukin-1 receptor-associated kinase 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES N#CC(C=N1)=CC=C1N2C3=NC(NC4CCOCC4)=C(OCCOCCO)C=C3N=C2
Molecular Weight 424.45

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Lavazais S, Jargosch M, Dupont S, Labéguère F, Menet C, Jagerschmidt C, Ohm F, Kupcsik L, Parent I, Cottereaux C et al..  (2023)  IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases..  Sci Transl Med,  15  (683): (eabj3289).  [PMID:36791209]

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