GLXC-26326 - 98%, high purity , CAS No.1226801-23-5, Inhibitor of ribosomal protein S6 kinase B1

Item Number

G610596

Grouped product items
SKU	Size	Availability	Price
G610596-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$179.90
G610596-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$589.90
G610596-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$949.90
G610596-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,899.90

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Basic Description

Synonyms	example 45 [WO2010056563A1];GLXC26326;LY-2780301;LY2780301
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of ribosomal protein S6 kinase B1
Product Description	LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.

Names and Identifiers

INCHI	InChI=1S/C25H27F4N7O/c1-34(2)9-10-36-13-20(16-3-4-19(26)18(11-16)25(27,28)29)32-23(36)15-5-7-35(8-6-15)24-17-12-21(37)33-22(17)30-14-31-24/h3-4,11,13-15H,5-10,12H2,1-2H3,(H,30,31,33,37)
InChi Key	YDFKZIGAUIKZGP-UHFFFAOYSA-N
Canonical SMILES	CN(C)CCN1C=C(N=C1C2CCN(CC2)C3=NC=NC4=C3CC(=O)N4)C5=CC(=C(C=C5)F)C(F)(F)F
Isomeric SMILES	CN(C)CCN1C=C(N=C1C2CCN(CC2)C3=NC=NC4=C3CC(=O)N4)C5=CC(=C(C=C5)F)C(F)(F)F
PubChem CID	46186926
Molecular Weight	517.52

PubChem CID

CAS Registry No.

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
G2426172	Certificate of Analysis	Apr 26, 2024	G610596
G2426173	Certificate of Analysis	Apr 26, 2024	G610596
G2426174	Certificate of Analysis	Apr 26, 2024	G610596
G2426175	Certificate of Analysis	Apr 26, 2024	G610596
G2426176	Certificate of Analysis	Apr 26, 2024	G610596
G2426177	Certificate of Analysis	Apr 26, 2024	G610596
G2426178	Certificate of Analysis	Apr 26, 2024	G610596
G2426179	Certificate of Analysis	Apr 26, 2024	G610596

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Basic Description