Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
G121415-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $19.90 | |
G121415-500mg | 500mg | In stock | $85.90 | |
G121415-1g | 1g | In stock | $153.90 | |
G121415-5g | 5g | In stock | $692.90 |
Synonyms | Glycyl-L-glutamic acid|7412-78-4|Gly-Glu|(S)-2-(2-Aminoacetamido)pentanedioic acid|N-Glycylglutamic acid|N-Glycyl-L-glutamic acid|(2S)-2-[(2-aminoacetyl)amino]pentanedioic acid|CHEMBL314532|(2S)-2-(2-aminoacetamido)pentanedioic acid|CHEBI:73801|L-Glutamic |
---|---|
Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | (2S)-2-[(2-aminoacetyl)amino]pentanedioic acid |
---|---|
INCHI | InChI=1S/C7H12N2O5/c8-3-5(10)9-4(7(13)14)1-2-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1 |
InChi Key | IEFJWDNGDZAYNZ-BYPYZUCNSA-N |
Canonical SMILES | C(CC(=O)O)C(C(=O)O)NC(=O)CN |
Isomeric SMILES | C(CC(=O)O)[C@@H](C(=O)O)NC(=O)CN |
WGK Germany | 3 |
PubChem CID | 99278 |
Molecular Weight | 204.18 |
Beilstein | 204.18 |
Reaxy-Rn | 1728201 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2205008 | Certificate of Analysis | Aug 22, 2022 | G121415 |
L2205009 | Certificate of Analysis | Aug 22, 2022 | G121415 |
L2205011 | Certificate of Analysis | Aug 22, 2022 | G121415 |
L2205587 | Certificate of Analysis | Aug 22, 2022 | G121415 |
J1421057 | Certificate of Analysis | Jul 15, 2022 | G121415 |
Sensitivity | Heat sensitive |
---|---|
Specific Rotation[α] | -7° (C=5,H2O) |
Melt Point(°C) | 158 °C(dec.) |
WGK Germany | 3 |
---|---|
Reaxy-Rn | 1728201 |
1. Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN. (2006) Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.. J Med Chem, 49 (12): (3636-44). [PMID:16759105] |
2. L W Haynes. (1991-04-01) Beta-endorphin C-terminal dipeptide elicits calcium influx and release of arachidonic acid metabolism in cortical neurones.. Biochemical Society transactions, 19 ((2)): (149S-149S). [PMID:1889543] |
3. S A Adibi. (1989-08-01) Intravenous use of glutamine in peptide form: clinical applications of old and new observations.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (89-92). [PMID:2503686] |
4. K Brand,W Fekl,J von Hintzenstern,K Langer,P Luppa,C Schoerner. (1989-08-01) Metabolism of glutamine in lymphocytes.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (29-33). [PMID:2569663] |
5. G B Koelle,U J Sanville,S J Wall. (1985-08-01) Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo.. Proceedings of the National Academy of Sciences of the United States of America, 82 ((15)): (5213-5217). [PMID:3860856] |
6. S Himmelseher,E Pfenninger,P Herrmann. (1996-07-01) Cerebrospinal and plasma amino acid concentrations after administration of i.v. glycyl-glutamine and glycyl-tyrosine containing amino acid solutions in humans.. JPEN. Journal of parenteral and enteral nutrition, 20 ((4)): (281-286). [PMID:8865110] |
7. C E Sänger-van de Griend. (1999-12-23) Enantiomeric separation of glycyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors.. Electrophoresis, 20 ((17)): (3417-3424). [PMID:10608709] |
8. Martin G Schmid,Maria Hölbling,Nikola Schnedlitz,Gerald Gübitz. (2004-11-25) Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors.. Journal of biochemical and biophysical methods, 61 ((1-2)): (1-10). [PMID:15560917] |
9. Christina Gatschelhofer,Martin G Schmid,Karin Schreiner,Thomas R Pieber,Frank M Sinner,Gerald Gübitz. (2006-03-25) Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).. Journal of biochemical and biophysical methods, 69 ((1-2)): (67-77). [PMID:16556463] |
10. Martin G Schmid,Karin Schreiner,Daniela Reisinger,Gerald Gübitz. (2006-08-10) Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column.. Journal of separation science, 29 ((10)): (1470-1475). [PMID:16894792] |
11. Theresa V Nguyen,David Fleisher,David E Smith. (2007-03-24) In vivo effects of glycyl-glutamate and glycyl-sarcosine on gabapentin oral absorption in rat.. Pharmaceutical research, 24 ((8)): (1538-1543). [PMID:17380260] |
12. Heike Hödl,Martin G Schmid,Gerald Gübitz. (2008-06-24) Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.. Journal of chromatography. A, 1204 ((2)): (210-218). [PMID:18571185] |
13. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912] |
14. Patricio Leyton,R Antonio Zárate,Sandra Fuentes,Carolina Paipa,Juan S Gómez-Jeria,Yessica Leyton. (2011-02-01) Influence of aluminum oxide on the prebiotic thermal synthesis of Gly-Glu-(Gly-Glu)(n) polymer.. Bio Systems, 104 ((2-3)): (118-126). [PMID:21277348] |
15. Zhanli Wang,Saisai Zhang,Hongwei Jin,Wei Wang,Jianxin Huo,Lishe Zhou,Yongfu Wang,Fengqin Feng,Liangren Zhang. (2011-05-31) Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation.. European journal of medicinal chemistry, 46 ((8)): (3428-3433). [PMID:21621881] |
16. Hyangmi Kim,Sang-Chul Yoon,Kwang-Ho Choi,Sung-Tae Kim,Jae-Bong Lee,Dong-Sun Kim,Ho Le Han,Kyung Sook Bae,Doo-Sang Park. (2016-12-29) Lacinutrix chionocetis sp. nov., isolated from gut of a red snow crab.. Archives of microbiology, 199 ((4)): (597-603). [PMID:28028566] |
17. Takayuki K Nemoto,Toshio Ono,Yuko Ohara-Nemoto. (2018-02-13) Establishment of potent and specific synthetic substrate for dipeptidyl-peptidase 7.. Analytical biochemistry, 548 (78-81). [PMID:29432753] |
18. Piia Liigand,Karl Kaupmees,Anneli Kruve. (2019-03-09) Influence of the amino acid composition on the ionization efficiencies of small peptides.. Journal of mass spectrometry : JMS, 54 ((6)): (481-487). [PMID:30849787] |
19. Yuko Ohara-Nemoto,Mohammad Tanvir Sarwar,Yu Shimoyama,Takeshi Kobayakawa,Takayuki K Nemoto. (2020-12-19) Preferential dipeptide incorporation of Porphyromonas gingivalis mediated by proton-dependent oligopeptide transporter (Pot).. FEMS microbiology letters, 367 ((24)): [PMID:33338236] |
20. G Ollenschläger,A Simmel,E Roth. (1989-08-01) Availability of glutamine from peptides and acetylglutamine for human tumor-cell cultures.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (40-42). [PMID:2761419] |
21. K Brand,J Von Hintzenstern,K Langer,W Fekl. (1987-09-01) Pathways of glutamine and glutamate metabolism in resting and proliferating rat thymocytes: comparison between free and peptide-bound glutamine.. Journal of cellular physiology, 132 ((3)): (559-564). [PMID:2888773] |
22. G B Koelle,U J Sanville,N S Thampi. (1987-10-01) Direct neurotrophic action of glycyl-L-glutamine in the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat.. Proceedings of the National Academy of Sciences of the United States of America, 84 ((19)): (6944-6947). [PMID:3477818] |
23. A Evans,M E Smith. (1997-01-01) Effect of beta-endorphin C-terminal peptides on glucose uptake in isolated skeletal muscles of the mouse.. Peptides, 18 ((1)): (165-167). [PMID:9114466] |
24. D L Owen,J S Morley,D M Ensor,J B Miles. (1998-06-25) The C-terminal tetrapeptide of beta-endorphin (MPF) enhances lymphocyte proliferative responses.. Neuropeptides, 32 ((2)): (131-139). [PMID:9639251] |
25. C Winckler,G Breves,M Boll,H Daniel. (1999-12-14) Characteristics of dipeptide transport in pig jejunum in vitro.. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 169 ((7)): (495-500). [PMID:10595319] |
26. Marina Ioudina,Etsuro Uemura. (2004-02-11) A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide.. Experimental neurology, 184 ((2)): (923-929). [PMID:14769384] |
27. Jemma Evans,Joanne Yap,Thillini Gamage,Lois Salamonsen,Evdokia Dimitriadis,Ellen Menkhorst. (2014-05-02) Galectin-7 is important for normal uterine repair following menstruation.. Molecular human reproduction, 20 ((8)): (787-798). [PMID:24782449] |
28. Robert S Jansen,Sunny Mahakena,Marcel de Haas,Piet Borst,Koen van de Wetering. (2015-10-31) ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.. The Journal of biological chemistry, 290 ((51)): (30429-30440). [PMID:26515061] |