Glyco-Obeticholic acid - ≥98.0%, high purity , CAS No.863239-60-5

Item Number

G648619

Grouped product items
SKU	Size	Availability	Price	Qty
G648619-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90

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Basic Description

Synonyms	Glyco-obeticholic acid\|863239-60-5\|Glyco-oca\|6-Egcdca\|Glycoobeticholic acid\|O2MZK6V9LQ\|UNII-O2MZK6V9LQ\|CHEMBL4072790\|Glycine, N-[(3a,5b,6a,7a)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]-\|Glycine, N-((3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-24-oxo
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist. In Vitro Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-[[(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
INCHI	InChI=1S/C28H47NO5/c1-5-18-22-14-17(30)10-12-28(22,4)21-11-13-27(3)19(7-8-20(27)25(21)26(18)34)16(2)6-9-23(31)29-15-24(32)33/h16-22,25-26,30,34H,5-15H2,1-4H3,(H,29,31)(H,32,33)/t16-,17-,18-,19-,20+,21+,22+,25+,26-,27-,28-/m1/s1
InChi Key	MTLPUOZJBFHNSO-FCWTVGIUSA-N
Canonical SMILES	CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)NCC(=O)O)C)C)O
Isomeric SMILES	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)NCC(=O)O)C)C)O
PubChem CID	121322333
Molecular Weight	477.68

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Basic Description